US2015093745A1PendingUtilityA1
Optoelectronic detection system
Assignee: MASSACHUSETTS INST TECHNOLOGYPriority: Feb 7, 2001Filed: Nov 13, 2014Published: Apr 2, 2015
Est. expiryFeb 7, 2021(expired)· nominal 20-yr term from priority
Inventors:James D. HarperRichard H. MathewsBernadette JohnsonMartha S. PetrovickAnn RundellFrances E. NargiTimothy StephensLinda Marie MendenhallMark A. HollisAlbert M. YoungTodd H. RiderEric SchwoebelTrina Rae Vian
G01N 21/75G01N 15/0205G01N 21/64G01N 2201/061G01N 33/56983G01N 21/76G01N 33/582G01N 2021/6439Y10S435/808G01N 33/54373G01N 33/54393Y10S436/805G01N 21/6428G01N 21/07G01N 33/554G01N 2201/025
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Claims
Abstract
The invention relates to optoelectronic systems for detecting one or more target particles. The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on the surface of each cell and are specific for the target particle to be detected, where binding of the target particle to the receptors directly or indirectly activates a reporter molecule, thereby producing a measurable optical signal.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1 . A method for detecting a target particle in a liquid sample comprising:
a) adding the liquid sample to a chamber; b) localizing the target particles within the chamber; c) adding emitting cells, comprising one or more receptors suitable for interaction with a target particle and emitter molecules that emit photons in response to one or more receptors interacting with the target particle, to form a mixture; d) localizing the emitter cells within a chamber; e) measuring for photon emission from the cells in the mixture.Join the waitlist — get patent alerts
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