US2015119369A1PendingUtilityA1

Clear, Greaseless Compositions

Assignee: CHEMSIL SILICONES INCPriority: Sep 25, 2002Filed: Oct 29, 2014Published: Apr 30, 2015
Est. expirySep 25, 2022(expired)· nominal 20-yr term from priority
A61K 31/165A61K 9/0014A61K 31/045A61K 47/34A61K 31/618A61K 31/125A61K 9/06A61K 31/07
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Claims

Abstract

The present invention relates to compositions including anhydrous compositions which include a dimethicone crosspolymer and/or dimethicone elastomer gum and one or more skin care products.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A topical analgesic composition comprising at least one high molecular weight silicone component having a molecular weight between about 100,000 Da and 100,000,000 Da, and at least one analgesic component, wherein the composition is substantially anhydrous, greaseless, and substantially clear or translucent. 
     
     
         2 . The greaseless analgesic composition of  claim 1  wherein the high molecular weight silicone component is selected from the group consisting of a dimethicone crosspolymer and a dimethicone gum. 
     
     
         3 . The greaseless analgesic composition of  claim 1  wherein said at least one analgesic component is selected from the group consisting of: methyl salicylate, salicylic acid, a salicylic acid derivative, camphor, menthol, eucalyptus oil, capsaicin, histamine dihydrochloride, methyl micotinate, wintergreen extract, eucalyptus extract, turpentine extract, a pharmaceutically acceptable salt of lidocaine, a pharmaceutically acceptable salt of bupivacaine, a pharmaceutically acceptable salt of chlorprocaine, a pharmaceutically acceptable salt of dibucaine, a pharmaceutically acceptable salt of etidocaine, a pharmaceutically acceptable salt of mepivacaine, a pharmaceutically acceptable salt of tetracaine, a pharmaceutically acceptable salt of dyclonine, a pharmaceutically acceptable salt of hexylcaine, a pharmaceutically acceptable salt of procaine, a pharmaceutically acceptable salt of cocaine, a pharmaceutically acceptable salt of ketamine, a pharmaceutically acceptable salt of pramoxine, a pharmaceutically acceptable salt of methdilizine, a pharmaceutically acceptable salt of trimeprazine, phenol and a steroidal or non-steriodal antiinflammatory agent. 
     
     
         4 . The greaseless analgesic composition of  claim 3  wherein said at least one analgesic component is selected from the group consisting of: methyl salicylate, salicylic acid, a salicylic acid derivative, camphor, menthol, eucalyptus oil, and capsaicin. 
     
     
         5 . The greaseless analgesic composition of  claim 1  further comprising at least one low molecular weight silicone having a measurable vapor pressure at room temperature. 
     
     
         6 . The greaseless analgesic composition of  claim 5  wherein said low molecular weight silicone is selected from the group consisting of a cyclic silicone and a non-cyclic silicone. 
     
     
         7 . The greaseless analgesic composition of  claim 6  wherein said low molecular weight silicone comprises a cyclomethicone. 
     
     
         8 . The greaseless analgesic composition of  claim 7  wherein said low molecular weight silicone comprises a cyclomethicone selected from the group consisting of octylmethylcyclotetrasiloxane, hexamethylcyclotrisiloxane and decamethylcyclopentasiloxane. 
     
     
         9 . The greaseless analgesic composition of  claim 6  wherein said low molecular weight silicone comprises a non-cyclic silicone selected from the group consisting of hexamethyldisiloxane and low molecular weight dimethicone. 
     
     
         10 . The greaseless analgesic composition of  claim 1  comprising a high molecular weight dimethicone component, a volatile low molecular weight component, and at least one analgesic component selected from the group consisting of methyl salicylate, salicylic acid, a salicylic acid derivative, camphor, menthol, eucalyptus oil and capsaicin. 
     
     
         11 . The greaseless analgesic composition of  claim 10  comprising at least two analgesic components selected from the group consisting of methyl salicylate, salicylic acid, a salicylic acid derivative, camphor, menthol, eucalyptus oil and capsaicin. 
     
     
         12 . The greaseless analgesic composition of  claim 1  comprising a capsaicin component dissolved in a alkyl fluid. 
     
     
         13 . The greaseless analgesic composition of  claim 12  comprising at least one low molecular weight silicone component. 
     
     
         14 . The greaseless analgesic composition of  claim 1 , in the form of a serum having a viscosity of from about 0.1 centistokes to about 3500 centistokes. 
     
     
         15 . A method of reducing pain in a mammal, comprising applying to a skin surface of said mammal a composition comprising the composition of  claim 1 , and permitting said applied composition to dry on said skin surface, wherein said high molecular weight silicone component forms substantially clear, water-resistant barrier on said skin surface after drying. 
     
     
         16 . A topical analgesic composition comprising at least one high molecular weight dimethicone component having a molecular weight between about 100,000 Da and 100,000,000 Da, and at least one analgesic component comprising an agent selected from the group consisting of selected from the group consisting of: methyl salicylate, salicylic acid, a salicylic acid derivative, camphor, menthol, eucalyptus oil, and capsaicin, wherein the composition is substantially anhydrous, greaseless, and substantially clear or translucent. 
     
     
         17 . The composition of  claim 16  wherein the composition further comprises at least one organic solvent. 
     
     
         18 . The composition of  claim 17  wherein the organic solvent comprises an isoparaffinic solvent. 
     
     
         19 . The composition of  claim 16  wherein the composition comprises a low molecular weight silicone having a measurable vapor pressure at room temperature. 
     
     
         20 . The composition of  claim 17  wherein the composition comprises a low molecular weight silicone having a measurable vapor pressure at room temperature.

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