US2015122738A1PendingUtilityA1
Blood Cleansing System & Method
Est. expiryNov 5, 2033(~7.3 yrs left)· nominal 20-yr term from priority
Inventors:Gwangseong Kim
A61M 1/362A61M 1/3683A61M 1/3679A61K 41/0057A61K 47/6803A61K 47/6849A61K 41/0071A61M 1/3686
36
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Claims
Abstract
The present invention relates to removing disease material from the blood of a patient. Specifically, the invention relates to using biological binders to trap disease material that is desired to be removed from the blood of a patient.
Claims
exact text as granted — not AI-modified1 . A method for removing disease causing material from blood, said method comprising the steps of:
attaching a photosensitizer to a binding agent to generate a conjugate material; injecting the conjugate material into a patient such that the conjugate material binds to a targeted material; circulating blood through an extracorporeal transparent tube; illuminating said tube with light to activate said photosensitizer, wherein the activation of said photosensitizer releases oxygen capable of causing cell death upon contact with the oxygen.
2 . The method of claim 1 , wherein said extracorporeal transparent tube is selected from a group of tubes comprising plastic tubes, polymer tubes, metallic tubes, silicone tubes.
3 . The method of claim 1 , wherein said extracorporeal transparent tube has an inner diameter of 1.02 mm.
4 . The method of claim 1 , wherein said extracorporeal transparent tube is modified with one or more additional binding agents to capture said targeted material.
5 . The method of claim 1 , wherein said binding agent is selected from a group of binding agents comprising one or more of a an antibody, a protein, a peptide, a molecule, or one or more of a material that binds to a pathogen, a cell, or a cancer cell.
6 . The method of claim 1 , wherein said targeted material is selected from a group of targeted material comprising pathogens, disease causing agents, viruses, bacteria, fungi, cancer cells, stem cell-like cancer cells, circulating tumor cells, microbial organisms.
7 . The method of claim 1 , wherein said photosensitizer is modified with a crosslinker to make it receptive to a binding agent.
8 . The method of claim 1 , wherein said wavelength of light to activate the photosensitizer is 660 nm.
9 . The method of claim 1 , wherein said conjugate material is used as an imaging agent.Join the waitlist — get patent alerts
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