Method for producing detoxified liver

Abstract

The present invention has demonstrated that microorganisms present in a liver can be killed by washing the bile duct and the portal vein with hot water, and then disinfecting the liver using a chlorine-based disinfectant. It has also been demonstrated that sterilizing effects can be enhanced by freezing the liver after disinfection with a chlorine-based disinfectant.

1 . A method for producing a liver sterilized of a microorganism, which comprises the steps of:
 (a) infusing hot water at a high pressure into either or both of the bile duct and the portal vein of a liver removed from a non-human animal; and   (b) infusing a chlorine-based disinfectant into either or both of the bile duct and the portal vein of the liver of step (a).   
     
     
         2 . The method of  claim 1 , further comprising the step of allowing a chlorine-based disinfectant to infiltrate into the liver. 
     
     
         3 . The method of  claim 1 , further comprising the step of freezing the liver. 
     
     
         4 . The method of  claim 1 , further comprising the steps of:
 (a) disinfecting the surface of the liver using a chlorine-based disinfectant; and   (b) freezing the liver of step (a).   
     
     
         5 . The method of  claim 4 , further comprising, prior to the step of freezing the liver, the step of allowing a chlorine-based disinfectant to infiltrate into the liver. 
     
     
         6 . The method of  claim 3 , further comprising the step of thawing the liver. 
     
     
         7 . The method of  claim 1 , wherein the microorganism is a microorganism that causes food poisoning. 
     
     
         8 . The method of  claim 7 , wherein the microorganism that causes food poisoning is a microorganism selected from the group consisting of  Campylobacter , pathogenic  Escherichia coli, Salmonella, Shigella, Aeromonas , and  Staphylococcus , and hepatitis E virus. 
     
     
         9 . A sterilized liver tissue obtained by the method of  claim 1 . 
     
     
         10 . The method of  claim 4 , further comprising the step of thawing the liver.