Filamentary devices for treatment of vascular defects

Abstract

Devices and methods for treatment of a patient's vasculature with some embodiments configured for delivery with a microcatheter for treatment of the cerebral vasculature of a patient. Some embodiments may include a permeable shell configured to occlude blood flow therethrough.

What is claimed is: 
     
         1 . A device for treating an aneurysm comprising:
 a resilient body made of plural filaments extending between a distal end and a proximal end of the body;   the body being deformable to a placement configuration for engaging the body with an aneurysm, the body being materially biased to an enlarged configuration in which the body presents a curvilinear surface to tissue abutting the body;   the proximal end being everted to form a concave proximal cavity defining a proximal periphery, a proximal hub assembly being disposed in the proximal cavity, wherein the proximal hub assembly is connectable to a tether and the proximal hub assembly includes a hub cavity for mechanically capturing a knot associated with the tether.   
     
     
         2 . The device of  claim 1 , wherein the proximal hub assembly defines a proximal end and the proximal end of the proximal hub assembly is recessed distally from the proximal periphery. 
     
     
         3 . The device of  claim 1 , the filaments including at least plural first filaments interwoven with at least plural second filaments, the first filaments having a first diameter and the second filaments having a second diameter. 
     
     
         4 . The device of  claim 1 , wherein the proximal hub assembly defines a proximal end and the proximal end of the proximal hub assembly is not recessed distally from the proximal periphery. 
     
     
         5 . The device of  claim 1 , comprising the tether and a heater coil surrounding a distal portion of the tether to break the tether responsive to energization of the heater coil. 
     
     
         6 . The device of  claim 5 , wherein the heater coil includes a close-wound electrical conductor and the close-wound electrical conductor is connected to first and second lead conductors configured for electrically energizing the close-wound heater coil, at least the first conductor extending away from the close-wound heater coil in a configuration that is less close-wound than the close-wound heater coil. 
     
     
         7 . The device of  claim 6 , the second conductor extending away from the close-wound heater coil in a configuration that is less close-wound than the close-wound heater coil. 
     
     
         8 . The device of  claim 1 , wherein the distal end is everted to form a distal cavity defining a distal periphery, and a distal hub is disposed in the distal cavity, the distal hub being connected to distal ends of at least some of the filaments. 
     
     
         9 . The device of  claim 1 , the filaments including at least plural first filaments interwoven with at least plural second filaments, the first filaments having a first diameter and the second filaments having a second diameter, the second diameter being different from the first diameter. 
     
     
         10 . The device of  claim 1 , wherein the proximal hub assembly defines a hub cavity for mechanically capturing a knot associated with the tether, the hub cavity being established by a proximal shoulder portion of the proximal hub assembly, the proximal shoulder portion including an opening through which the tether can extend but through which opening the knot cannot pass. 
     
     
         11 . The device of  claim 8 , wherein the distal hub defines a distal end and the distal end of the distal hub is recessed proximally from the distal periphery. 
     
     
         12 . The device of  claim 10 , wherein the knot is secured by bonding to a distal end of the tether within the hub cavity. 
     
     
         13 . The device of  claim 10 , wherein the knot is secured by bonding to proximal ends of the filaments. 
     
     
         14 . A device for treating an aneurysm comprising:
 a resilient body made of plural filaments extending between a distal end and a proximal end of the body;   the body being deformable to a placement configuration ftr engaging the body with an aneurysm, the body being materially biased to an enlarged configuration in which the body presents a curvilinear surface to tissue abutting the body;   a proximal hub assembly disposed proximally on the body, wherein the proximal hub assembly is connected to a tether;   a heater coil surrounding a distal portion of the tether to break the tether responsive to energization of the heater coil, wherein the heater coil includes a close-wound electrical conductor and the close-wound electrical conductor is connected to first and second lead conductors configured for electrically energizing the close-wound heater coil.   
     
     
         15 . The device of  claim 14 , wherein the proximal end is everted to form a concave proximal cavity defining a proximal periphery. 
     
     
         16 . The device of  claim 14 , wherein the proximal hub assembly includes a hub cavity for mechanically capturing a knot associated with the tether. 
     
     
         17 . The device of  claim 15 , wherein the proximal hub assembly defines a proximal end and the proximal end of the proximal hub assembly is recessed distally from the proximal periphery. 
     
     
         18 . The device of  claim 14 , the filaments including at least plural first filaments interwoven with at least plural second filaments, the first filaments having a first diameter and the second filaments having a second diameter. 
     
     
         19 . The device of  claim 15 , wherein the proximal hub assembly defines a proximal end and the proximal end of the proximal hub assembly is not recessed distally from the proximal periphery. 
     
     
         20 . The device of  claim 14 , comprising a distal hub disposed at the distal end of the body and connected to at least some of the filaments. 
     
     
         21 . The device of  claim 20 , wherein the distal end is everted to form a distal cavity defining a distal periphery, and a distal hub is disposed in the distal cavity. 
     
     
         22 . Apparatus comprising:
 resilient body composed of filaments with respective proximal and distal ends;
 a recessed distal hub securing the distal ends; 
 a recessed proximal hub assembly securing the proximal ends; 
 a tether secured to the proximal hub assembly; 
 an electrically energizable heater coil coiled around a distal segment of the tether to break the tether when the heater coil is energized; and 
 insulative tubing covering the heater coil. 
   
     
     
         23 . The device of  claim 1 , wherein the body includes plural first filaments including platinum and plural second filaments made of only nitinol. 
     
     
         24 . The device of  claim 14 , wherein the body includes plural first filaments including platinum and plural second filaments made of only nitinol.