US2015150873A1PendingUtilityA1
Novel ring-substituted n-pyridinyl amides as kinase inhibitors
Est. expiryMay 21, 2032(~5.9 yrs left)· nominal 20-yr term from priority
Inventors:Matthew BurgerJoseph E. Drumm IiiGisele NishiguchiAlice RicoRobert Lowell SimmonsBenjamin R. TaftHuw Tanner
A61P 43/00A61P 37/02A61P 37/00A61P 35/02A61P 35/00A61P 29/00A61P 1/04C07D 409/14A61K 31/4545C07D 213/81A61K 31/675C07D 401/14A61K 31/506C07F 9/65583C07D 407/14C07D 403/12C07D 403/14C07D 417/14C07D 417/12C07D 401/12A61K 31/4439C07D 405/14A61K 31/444A61K 45/06
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Abstract
The present invention provides a compound of formula (A): as described herein, and pharmaceutically acceptable salts, enantiomers, rotamers, tautomers, or racemates thereof. Also provided are methods of treating a disease or condition mediated by PIM kinase using the compounds of Formula I, and pharmaceutical compositions comprising such compounds.
Claims
exact text as granted — not AI-modified1 - 21 . (canceled)
22 . A method of treating a disease or condition selected from carcinoma of the lungs, pancreas, thyroid, ovaries, bladder, breast, prostate or colon, melanoma, myeloid leukemia, multiple myeloma, erythro leukemia, villous colon adenoma, and osteosarcoma, comprising administering to a subject in need thereof a therapeutically effective amount of a compound selected from:Cited by (0)
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