Antimicrobial coatings

Abstract

The disclosure provides polymers having antimicrobial activity and articles with the polymers coated thereon. The polymers include a first pendant group comprising a first quaternary ammonium component, a second pendant group comprising a nonpolar component, and a third pendant group comprising an organosilane component. The disclosure also includes methods of coating articles with the antimicrobial polymers. The methods further include the use of adhesion-promoting reagents.

What is claimed is: 
     
         1 . An article, comprising:
 a touch-sensitive substrate comprising a surface;   a first layer coated on the surface, the first layer comprising an adhesion-promoting reagent; and   a second layer coated on the first layer, the second layer comprising an organic polymer having a plurality of pendant groups comprising
 a first pendant group comprising a first quaternary ammonium component; 
 a second pendant group comprising a nonpolar component; 
 a third pendant group comprising a first organosilane component. 
   
     
     
         2 . The article of  claim 1 , wherein the adhesion-promoting reagent is selected from the group consisting of 3-triethoxysilyl-N-(1,3-dimethyl-butyliden)propylamine, N-phenyl-3-aminopropyltrimethoxysilane, and 3-[2-(2-aminoethylamino)ethylamino]propyl-trimethoxysilane, 3-aminopropyltrimethoxysilane, 3-aminopropyltriethoxysilane, 3-(2-aminoethyl)aminopropyltrimethoxysilane, (aminoethylaminomethyl)phenethyltrimethoxysilane, (aminoethylaminomethyl)phenethyltriethoxysilane, N-(2-aminoethyl)-3-aminopropylmethyldimethoxysilane, bis-(γ-triethoxysilylpropyl)amine, N-(2-aminoethyl)-3-aminopropyltributoxysilane, 6-(aminohexylaminopropyl)trimethoxysilane, 4-aminobutyltrimethoxysilane, 4-aminobutyltriethoxysilane, p-(2-aminoethyl)phenyltrimethoxysilane, 3-aminopropyltris(methoxyethoxyethoxy)silane, 3-aminopropylmethyldiethoxysilane, tetraethoxysilane and oligomers thereof, methyltriethoxysilane and oligomers thereof, an oligomeric aminosilane, 6,3-(N-methylamino)propyltrimethoxysilane, N-(2-aminoethyl)-3-aminopropylmethyldimethoxysilane, N-(2-aminoethyl)-3-aminopropylmethyldiethoxysilane, N-(2-aminoethyl)-3-aminopropyltrimethoxysilane, N-(2-aminoethyl)-3-aminopropyltriethoxysilane, 3-aminopropylmethyldiethoxysilane, 3-aminopropylmethyldimethoxysilane, 3-aminopropyldimethylmethoxysilane, and 3-aminopropyldimethylethoxysilane. 
     
     
         3 . An article made by the process of:
 forming a first composition of an organic polymer in organic solvent, the polymer having a plurality of pendant groups comprising,
 a first pendant group comprising a first quaternary ammonium component, 
 a second pendant group comprising a nonpolar component, and 
 a third pendant group comprising a first organosilane component; 
   mixing a second quaternary ammonium component with the first composition to form a first mixture; and   contacting the first mixture with a substrate under conditions suitable to form covalent linkages between the organic polymer, the substrate, and the second quaternary ammonium component.