US2015272997A1PendingUtilityA1

Mesenchymal Stem Cells and Uses Therefor

Assignee: MESOBLAST INTERNAT SÁRLPriority: Mar 22, 2004Filed: Jun 15, 2015Published: Oct 1, 2015
Est. expiryMar 22, 2024(expired)· nominal 20-yr term from priority
A61P 37/08A61P 7/06A61P 9/00A61P 35/00A61P 5/14A61P 3/10A61P 7/04A61P 37/02A61P 37/06A61P 43/00A61P 37/00A61P 29/00A61P 25/00A61P 27/02A61P 17/06A61K 35/28C12N 5/0667A61P 13/08A61P 1/04C12N 5/0664C12N 5/0662A61P 17/00C12N 5/0666A61P 1/00A61P 1/02A61P 11/00A61P 17/14C12N 5/0663A61P 19/02C12N 5/0665C12N 5/0668A61P 19/08A61K 38/2066A61K 45/06A61K 2035/124A61K 38/2026A61P 17/02A61K 35/12Y02A50/30
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Claims

Abstract

Methods of treating autoimmune diseases, allergic responses, cancer, or inflammatory diseases in an animal, promoting wound healing, repairing epithelial damage and promoting angiogenesis in an organ or tissue of an animal by administering to the animal mesenchymal stem cells in an effective amount.

Claims

exact text as granted — not AI-modified
1 . A method of treating autoimmune encephalomyelitis, multiple sclerosis or inflammatory bowel diseases in an animal comprising
 administering genetically unmanipulated mesenchymal stem cells.   
     
     
         2 . The method of treating autoimmune encephalomyelitis, multiple sclerosis or inflammatory bowel diseases in an animal of  claim 1 , wherein the genetically unmanipulated mesenchymal stem cells are administered in combination with an anti-inflammatory drug. 
     
     
         3 . The method of treating autoimmune encephalomyelitis, multiple sclerosis or inflammatory bowel diseases in an animal of  claim 1 , wherein the animal is a mammal. 
     
     
         4 . The method of treating autoimmune encephalomyelitis, multiple sclerosis or inflammatory bowel diseases in an animal of  claim 3 , wherein the mammal is a human. 
     
     
         5 . The method of treating autoimmune encephalomyelitis, multiple sclerosis or inflammatory bowel diseases in an animal of  claim 1 , wherein the inflammatory bowel disease is Crohn's Disease. 
     
     
         6 . The method of treating autoimmune encephalomyelitis, multiple sclerosis or inflammatory bowel diseases in an animal of  claim 1 , wherein the inflammatory bowel disease is ulcerative colitis. 
     
     
         7 . The method of treating autoimmune encephalomyelitis, multiple sclerosis or inflammatory bowel diseases in an animal of  claim 1 , wherein the inflammatory bowel disease is Graft Versus Host Disease of the gut.

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