US2015290267A1PendingUtilityA1

Topical treatments incorporating cannabis sp. derived botanical drug product

Assignee: SEKURA RONALD DPriority: Sep 26, 2013Filed: Jun 25, 2015Published: Oct 15, 2015
Est. expirySep 26, 2033(~7.2 yrs left)· nominal 20-yr term from priority
A61K 36/3482A61K 31/658A61K 31/05A61K 45/06A61K 31/573A61K 31/352A61K 36/185A61K 31/235A61P 17/06A61K 47/44A61K 36/61A61K 36/00A61Q 19/00A61K 31/245A61K 31/047A61K 9/0043A61Q 5/02A61K 9/06A61K 9/0034A61Q 5/006A61K 31/045A61Q 19/001A61K 31/085A61K 9/08A61K 9/0014A61K 8/498A61K 47/12A61K 31/618A61K 31/12
60
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Claims

Abstract

A topical formulation comprising a Cannabis derived botanical drug product, wherein the concentration of tetrahydrocannabinol, cannabidiol, or both in the topical formulation is greater than 2 milligrams per kilogram.

Claims

exact text as granted — not AI-modified
1 : A topical formulation comprising a  Cannabis  derived botanical drug product, wherein the concentration of tetrahydrocannabinol in the topical formulation is greater than 2 milligrams per kilogram. 
     
     
         2 : A topical formulation according to  claim 1 , which further comprises hydrocortisone or any steroid within Groups I to VII in the US classification system in a therapeutically effective amount. 
     
     
         3 : A topical formulation according to  claim 1 , which further comprises an antibiotic compound in a therapeutically effective amount. 
     
     
         4 : A topical formulation according to  claim 1 , which further comprises an antiseptic compound in a therapeutically effective amount. 
     
     
         5 : A topical formulation according to  claim 1 , which further comprises an antifungal compound in a therapeutically effective amount. 
     
     
         6 : A topical formulation according to  claim 1 , which further comprises an anti-acne agent in a therapeutically effective amount. 
     
     
         7 : A topical formulation according to  claim 1 , which further comprises a soothing, smoothing, moisturizing or protective agent in a therapeutically effective amount. 
     
     
         8 : A topical formulation according to  claim 1 , which further comprises a UV-absorbing compound in a therapeutically effective amount. 
     
     
         9 : A topical formulation according to  claim 1 , which further comprises an analgesic compound in a therapeutically effective amount. 
     
     
         10 : A topical formulation according to  claim 1 , which further comprises an anti-viral compound in a therapeutically effective amount. 
     
     
         11 : A method of treating a dermatological disease, which comprises applying the topical formulation according to  claim 1  to skin affected with a dermatological disease. 
     
     
         12 : A method according to  claim 11 , wherein said dermatological disease is psoriasis. 
     
     
         13 : A topical formulation comprising a  Cannabis  derived botanical drug product, wherein the concentration of cannabidiol in the topical formulation is greater than 2 milligrams per kilogram. 
     
     
         14 : A topical formulation according to  claim 13 , which further comprises hydrocortisone or any steroid within Groups I to VII in the US classification system in a therapeutically effective amount. 
     
     
         15 : A topical formulation according to  claim 13 , which further comprises an antibiotic compound in a therapeutically effective amount. 
     
     
         16 : A topical formulation according to  claim 13 , which further comprises an antiseptic compound in a therapeutically effective amount. 
     
     
         17 : A topical formulation according to  claim 13 , which further comprises an antifungal compound in a therapeutically effective amount. 
     
     
         18 : A topical formulation according to  claim 13 , which further comprises an anti-acne agent in a therapeutically effective amount. 
     
     
         19 : A topical formulation according to  claim 13 , which further comprises a soothing, smoothing, moisturizing or protective agent in a therapeutically effective amount. 
     
     
         20 : A topical formulation according to  claim 13 , which further comprises a UV-absorbing compound in a therapeutically effective amount. 
     
     
         21 : A topical formulation according to  claim 13 , which further comprises an analgesic compound in a therapeutically effective amount. 
     
     
         22 : A topical formulation according to  claim 13 , which further comprises an anti-viral compound in a therapeutically effective amount. 
     
     
         23 : A method of treating a dermatological disease, which comprises applying the topical formulation according to  claim 13  to skin affected with a dermatological disease. 
     
     
         24 : A method according to  claim 23 , wherein said dermatological disease is psoriasis. 
     
     
         25 : A topical formulation comprising a  Cannabis  derived botanical drug product, wherein the concentration of each, cannabidiol and tetrahydrocannabinol, in the topical formulation is greater than 2 milligrams per kilogram. 
     
     
         26 : A topical formulation according to  claim 25 , which further comprises hydrocortisone or any steroid within Groups I to VII in the US classification system in a therapeutically effective amount. 
     
     
         27 : A topical formulation according to  claim 26 , which further comprises an antibiotic compound in a therapeutically effective amount. 
     
     
         28 : A topical formulation according to  claim 26 , which further comprises an antiseptic compound in a therapeutically effective amount. 
     
     
         29 : A topical formulation according to  claim 26 , which further comprises an antifungal compound in a therapeutically effective amount. 
     
     
         30 : A topical formulation according to  claim 26 , which further comprises an anti-acne agent in a therapeutically effective amount. 
     
     
         31 : A topical formulation according to  claim 26 , which further comprises a soothing, smoothing, moisturizing or protective agent in a therapeutically effective amount. 
     
     
         32 : A topical formulation according to  claim 26 , which further comprises a UV-absorbing compound in a therapeutically effective amount. 
     
     
         33 : A topical formulation according to  claim 26 , which further comprises an analgesic compound in a therapeutically effective amount. 
     
     
         34 : A topical formulation according to  claim 26 , which further comprises an anti-viral compound in a therapeutically effective amount. 
     
     
         35 : A method of treating a dermatological disease, which comprises applying the topical formulation according to  claim 26  to skin affected with a dermatological disease. 
     
     
         36 : A method according to  claim 35 , wherein said dermatological disease is psoriasis. 
     
     
         37 : A topical formulation comprising a  Cannabis  extract and at least one member selected from the group consisting of hydrocortisone or any steroid within Groups I to VII in the US classification system; an antibiotic compound; an antiseptic compound; an antifungal compound; an anti-acne agent; a soothing, smoothing, moisturizing or protective agent; a UV-absorbing compound; an analgesic compound; and an anti-viral compound,
 wherein the concentration of tetrahydrocannabinol, cannabidiol, or both in the topical formulation is greater than 2 milligrams per kilogram, wherein, when both tetrahydrocannabinol and cannabidiol are present in the topical formulation, the concentration of each of tetrahydrocannabinol and cannabidiol is greater than 2 milligrams per kilogram, and   said topical formulation obtained by dispersing the  Cannabis  extract in a water-in-oil emulsion, an oil-in-water emulsion, a wax-in-oil base, or an oil-in-wax base that comprises said at least one at least one member selected from the group consisting of hydrocortisone or any steroid within Groups I to VII in the US classification system; an antibiotic compound; an antiseptic compound; an antifungal compound; an anti-acne agent; a soothing, smoothing, moisturizing or protective agent; a UV-absorbing compound; an analgesic compound; and an anti-viral compound.   
     
     
         38 : The topical formula according to  claim 37 , wherein said  Cannabis  extract comprises an extract of  cannabis sativa  or  cannabis  indicia. 
     
     
         39 : The topical formula according to  claim 37 , wherein said topical formulation adjuvant is at least one member selected from the group consisting of capsaicin, benzocaine, lidocaine, camphor, benzoin resin, methylsalicate, triethanolamine salicylate, hydrocortisone, and salicylic acid.

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