US2015291616A1PendingUtilityA1

Bryoid compositions, methods of making and use thereof

Assignee: APHIOS CORPPriority: Nov 27, 2012Filed: Nov 26, 2013Published: Oct 15, 2015
Est. expiryNov 27, 2032(~6.4 yrs left)· nominal 20-yr term from priority
A61P 25/14A61P 31/22A61P 31/18A61P 25/28A61P 25/16A61P 35/00A61P 31/12A61P 27/06A61K 31/365C07D 493/22A61P 25/00
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Claims

Abstract

Embodiments of the present invention feature novel Bryoid compositions, methods of making and methods of treating disease

Claims

exact text as granted — not AI-modified
1 . A first Bryoid composition having a molecular weight of approximately 896-898 Amu (Mass+Sodium) and 873-875 Amu (monoisotopic mass) having a purity of approximately 50% to a crystal forming purity. 
     
     
         2 . The first Bryoid composition of  claim 1  having a measured mass plus sodium of 897.2 Amu and a measured monoisotopic mass of 874.2 Amu. 
     
     
         3 . A second Bryoid composition having a molecular weight of approximately 910-912 Amu (Mass+Sodium) and 888-890 Amu (monoisotopic mass) having a purity of approximately 50% to a crystal forming purity. 
     
     
         4 . The second Bryoid composition of  claim 3  having a measured mass plus sodium of 911.5 Amu and a measured monoisotopic mass of 888.9 Amu. 
     
     
         5 . A third Bryoid composition having a molecular weight of approximately 868-870 Amu (Mass+Sodium) and 846-848 Amu (monoisotopic mass) having a purity of approximately 50% to a crystal forming purity. 
     
     
         6 . The third Bryoid composition of  claim 5  having a measured mass plus sodium of 869.5 Amu and a measured monoisotopic mass of 846.6 Amu. 
     
     
         7 . A fourth Bryoid composition having a molecular weight of approximately 895-897 Amu (Mass+Sodium) and 872-874 Amu (monoisotopic mass) having a purity of approximately 50% to a crystal forming purity. 
     
     
         8 . The fourth Bryoid composition of  claim 7  having a measured mass plus sodium of 895.5 Amu and a measured monoisotopic mass of 872.6 Amu. 
     
     
         9 . A method of making a Bryoid composition comprising the steps isolating a Bryoid composition from a source of Bryoids and purifying the Bryoid composition to a purity of 50% and a crystal forming purity said Bryoid composition selected from the group of Bryoids consisting of the first Bryoid, second Bryoid, third Bryoid and fourth Bryoid. 
     
     
         10 . A method of treating a disease responsive to Bryoid compositions comprising the step of administering an effective amount of a bryoid composition selected from the group of Bryoids consisting of the first Bryoid, second Bryoid, third Bryoid and fourth Bryoid.

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