A use of the mixture of a salt and sugar in the manufacture of a medicament employed for treating Lax vegina syndrome or colpoxerosis disease in an mammal

Abstract

The use of the mixture of a salt and sugar in the manufacture of a medicament employed for treating lax vagina syndrome or colpoxerosis disease in a mammal. Various tests, vaginal smooth muscle contractility test using New Zealand White Rabbit; (Experimental example 1); the effect on the vagina contractility in volunteers by using perinometer (Experimental example 2); and the effect on the colpoxerosis disease in volunteers (Experimental example 3), showed improving effect on the contractility of vagina tissue and colpoxerosis disease. Accordingly, the combination can be useful in treating or preventing lax vagina syndrome or colpoxerosis disease.

1 . An external composition comprising a combination of salt and sugar as an active ingredient in an amount effective to treat lax vagina syndrome or colpoxerosis disease. 
     
     
         2 . The composition according to  claim 1  wherein said salt is an imported or native processed salt, refined salt or an un-refined salt. 
     
     
         3 . The composition according to  claim 2  wherein said processed salt is a melted salt prepared by melting an un-refined salt at a temperature ranging from 200 to 2000° C., for a period ranging from 2 hours to 7 days. 
     
     
         4 . (canceled) 
     
     
         5 . (canceled) 
     
     
         6 . The composition according to  claim 1  wherein said combination of salt and sugar is a combination of salt and sugar mixed ratio of 1:1 to 1:30 (w/w). 
     
     
         7 . (canceled) 
     
     
         8 . The composition according to  claim 1  wherein the composition is a topical preparation selected from the group consisting of cleansing liquid, gel, jelly, foam, cream, ointment, lotion, balm, patch, paste, spray solution, and aerosol; or an insert preparation selected from the group consisting of vaginal tablet, vaginal capsule, vaginal film, vaginal sponge, tampon, and pad. 
     
     
         9 . The composition according to  claim 8  wherein the composition is selected from the group consisting of vaginal tablet and cleansing liquid. 
     
     
         10 . (canceled)