US2015360147A1PendingUtilityA1

Benzimidazole Compounds And Their Use As Chromatographic Ligands

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Assignee: MILLIPORE U K LTDPriority: Jan 11, 2007Filed: Aug 27, 2015Published: Dec 17, 2015
Est. expiryJan 11, 2027(~0.5 yrs left)· nominal 20-yr term from priority
C08B 37/0039C08B 37/00B01D 15/3828C07K 16/065C07K 1/22C07D 403/04C07D 235/06B01J 20/3255B01J 20/3246B01J 20/3242B01J 20/3219B01J 20/289B01D 15/3804B01D 15/38B01D 2015/3838
44
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Claims

Abstract

The present invention provides a new method for isolation and/or purification of immunoglobulins from a solution containing one or more immunoglobulins using a solid phase matrix represented by the formula: M-SP-L, wherein M is designates a matrix backbone, SP designates a spacer and L designates a substituted benzimidazole ligand.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 .- 11 . (canceled) 
     
     
         12 . A compound represented by the following structural formula: 
       
         
           
           
               
               
           
         
       
     
     
         13 . A solid phase matrix represented by the general formula:
   M-SP-L,   wherein M designates the matrix backbone, SP designates a spacer, and L designates a ligand represented by the following structural formulas:   
       
         
           
           
               
               
           
         
       
     
     
         14 . The solid phase matrix of claim  2 , wherein the matrix backbone is agarose. 
     
     
         15 . The solid phase matrix of claim  2 , wherein the spacer SP is represented by the following formula:
 —(O—CH 2 CH(OH)—CH 2 ) m —, wherein m is an integer from 1 to 10.

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