US2015375227A1PendingUtilityA1
Microfabricated Crossflow Devices and Methods
Est. expirySep 15, 2020(expired)· nominal 20-yr term from priority
B01L 3/502784B01L 3/502761B01L 2200/0652G01N 15/1492G01N 2015/1481C12Q 1/68B01L 2200/0647B01L 2400/0487Y10T436/118339B01L 2400/0638G01N 15/1459C12M 1/34G01N 2015/1411B01L 2400/0421G01N 33/54366B01L 2400/0418Y10T436/143333B01L 3/502715B01L 2200/0673G01N 15/1484G01N 15/1404B01L 2400/0484G01N 15/1434B01L 2200/12G01N 35/08B01L 2400/0454B01L 2300/123B01L 3/502707G01N 2015/1006B01L 2300/0864B01L 2300/0816B01L 2300/0654B01L 2400/0481B01L 2300/12G01N 2015/019G01N 2015/1028G01N 15/01G01N 15/149
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Abstract
This invention provides microfabricated devices and methods for detecting, analyzing and sorting biological materials and particles. Droplets containing the particles are provided in an extrusion fluid, passed through a detection region, and then directed into a branch channel according to predetermined characteristics. For example, cells or viral particles contained in droplets of aqueous solvent are flowed past a detector in the nonpolar extrusion fluid decane, and routed into a selected branch channel for subsequent analysis or use.
Claims
exact text as granted — not AI-modified1 . A microfluidic device comprising a main channel, and at least one inlet region in communication with the main channel at a droplet extrusion region.
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