US2016016912A1PendingUtilityA1

Bendamustine derivatives and methods of using same

Assignee: IGNYTA INCPriority: Nov 12, 2012Filed: Sep 28, 2015Published: Jan 21, 2016

Est. expiryNov 12, 2032(~6.3 yrs left)· nominal 20-yr term from priority

Inventors:Roger P. Bakale Peter D. Brown Jian-Xie Chen Anthony S. Drager Rachel Y. Labell Robert E. Mckean Piyush R. Patel Renee Caroline Roemmele

A61K 9/14A61K 31/4184A61P 35/00A61K 47/42A61P 35/02C07D 235/16

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Abstract

The present invention is directed to bendamustine esters and bendamustine amides and their use for the treatment of cancer.

Claims

exact text as granted — not AI-modified

What is claimed: 
     
         1 . A compound of formula (I) 
       
         
           
           
               
               
           
         
         wherein R 1  is C 6 -C 24  alkyl, or a pharmaceutically acceptable salt thereof.

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