US2016206575A1PendingUtilityA1

Inhibition of Biofilm Organisms

54
Assignee: NOVABIOTICS LTDPriority: Mar 31, 2009Filed: Mar 28, 2016Published: Jul 21, 2016
Est. expiryMar 31, 2029(~2.7 yrs left)· nominal 20-yr term from priority
A61K 31/145A61P 31/00A61L 2300/424A61L 15/46A61L 2300/45A61L 15/44A61L 31/16A61L 2300/254A61L 27/54A61K 38/08A61P 31/04A61K 38/1729A61L 29/16A61L 2300/404A01N 33/08
54
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Claims

Abstract

The present invention relates to a product comprising at least two antibiofilm agents wherein at least one of the antibiofilm agents is an antimicrobial peptide. The second antibiofilm agent is cysteamine. There is also provided the use of the product in the treatment of a microbial infection.

Claims

exact text as granted — not AI-modified
1 .- 51 . (canceled) 
     
     
         52 . A method of treating a biofilm in a patient, by prophylaxis or therapy, comprising administering to the patient a mucolytic agent wherein the mucolytic agent is cysteamine. 
     
     
         53 . The method of  claim 52  wherein the patient has cystic fibrosis. 
     
     
         54 . The method of  claim 52  wherein the biofilm is associated with an infection in cystic fibrosis. 
     
     
         55 . A method of treating a condition associated with cystic fibrosis, by prophylaxis or therapy, in a patient comprising administering to said patient a mucolytic agent wherein the mucolytic agent is cysteamine. 
     
     
         56 . The method of  claim 55  wherein the mucolytic agent is administered alone. 
     
     
         57 . A method of treating a bacterial infection in a cystic fibrosis patient comprising administering to said patient an amount of cysteamine effective to treat said infection.

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