US2016235794A1PendingUtilityA1
Lipid extract of passiflora seeds
Est. expirySep 25, 2033(~7.2 yrs left)· nominal 20-yr term from priority
A61K 8/9789A61Q 19/04A61K 31/01A23V 2002/00A61K 9/0014A23L 33/105A61K 9/06A61K 2236/55A61Q 19/00A61K 2800/592A23D 9/007C11B 3/02A61Q 19/08A61K 8/63A61K 31/355A61Q 19/06A61K 9/107A61K 31/202A61P 17/02A61Q 19/007C11B 3/12C11B 3/006A61K 31/56A61K 8/922C11B 3/001A61K 8/31A61K 31/20A61K 2800/80A61Q 19/004A61K 31/201A61K 8/678A61K 8/361A61K 36/185A61K 2236/39C12Y 302/01001C11B 1/10A23L 1/3002A61K 8/97
60
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Claims
Abstract
The invention relates to a lipid extract of the seeds of passion fruit, Passiflora incarnata and/or Passiflora edulis , preferably P. edulis , characterised in that said lipid extract is an oil of passion fruit seeds concentrated in its unsaponifiable fraction, containing between 3 wt. % and 100 wt. % of unsaponifiable matter in relation to the total weight of the extract. The invention also relates to a method for preparing such an extract and to a composition comprising said extract, especially for the use thereof in a dermatological or pharmaceutical composition or as a food.
Claims
exact text as granted — not AI-modified1 .- 21 . (canceled)
22 . A lipid extract from Passiflora seeds, Passiflora incarnate , or Passiflora edulis , or a combination of these species, wherein said lipid extract is oil of Passiflora seeds concentrated in its unsaponifiable fraction containing 3 to 100 weight % of unsaponifiables relative to the total weight of the extract.
23 . A lipid extract according to claim 22 , wherein said lipid extract is from Passiflora edulis.
24 . An extract according to claim 22 , wherein the lipid extract is oil of Passiflora seeds concentrated in its unsaponifiable fraction having the following characteristics:
Fatty fraction (weight % relative to total oil weight)
C14 (myristic acid)
≦1.0
C16 (palmitic acid)
5.0-15.0
C16′ (5-hexadecenoic acid)
≦1.0
C18 (stearic acid)
≦5.0
C18′ (oleic acid)
10.0-20.0
C18″ (linoleic acid)
60.0-80.0
C18″′ (α-linolenic acid)
<1.0
C20 (arachidic acid)
≦1.0
C20′ (eicasenoic acid)
≦1.0
C22 (behenic acid)
≦1.0
Total unsaponifiable content (g/100 g)
3.0-15.0
25 . An extract according to claim 22 , wherein the lipid extract is an unsaponifiable having the following characteristics:
Unsaponifiable fraction (weight % relative to
total weight of the unsaponifiable fraction)
Tocopherol content
0.1%-3.0%
Tocotrienol content
5.0%-25%
Sterol content
30%-60%
Squalene content
10%-35%
Non-identified
<30%
26 . An extract according to claim 22 , wherein the lipid extract is obtained using a process comprising the following steps in the order shown:
a) molecular distillation of crude or refined Passiflora oil to yield an oil concentrated in unsaponifiable; b) optionally, extraction of the unsaponifiable; c) recovery of the oil concentrated in unsaponifiable obtained at step a) or of the extracted unsaponifiable obtained after step b).
27 . An extract according to claim 26 , wherein step b) comprises the following steps in the order shown:
i. saponification of the Passiflora oil concentrated in its unsaponifiable fraction obtained after step a); ii. followed by extraction of the unsaponifiable using a suitable solvent.
28 . A method to prepare an extract according to claim 22 , comprising the following steps in the order shown:
a) molecular distillation of crude or refined Passiflora oil to yield an oil concentrated in unsaponifiable; b) optionally, extraction of the unsaponifiable; c) recovery of the oil concentrated in unsaponifiable obtained after step a) or of the unsaponifiable obtained after step b).
29 . A method according to claim 28 wherein step b) comprises the following successive steps:
i. saponification of the Passiflora oil concentrated in its unsaponifiable fraction obtained after step a);
ii. followed by extraction of the unsaponifiable using a suitable solvent.
30 . A method according to claim 29 , wherein the molecular distillation step a) is performed using molecular distillation units of centrifugal type or molecular devices of scraped film type.
31 . A composition comprising as active ingredient a lipid extract of Passiflora seeds according to claim 22 and a suitable excipient.
32 . The composition according to claim 31 , comprising 0.01 weight % to 20 weight % of said lipid extract relative to the total weight of the composition.
33 . The composition according to claim 31 , wherein the excipient is dermatologically or pharmaceutically acceptable.
34 . A functional food comprising a composition according to claim 31 .
35 . A method to stimulate, restore or regulate the metabolism of skin or mucosa cells or to prevent or treat disorders related to dermal tissue, or a combination of thereof, comprising administering the extract of claim 22 to a person in a need thereof.
36 . A method according to claim 35 , wherein the extract is administrated:
as anti-aging agent; as healing agent; to prevent deterioration of and/or to maintain homeostasis of the skin or mucosae; as antioxidant agent; as anti-inflammatory agent; as slimming or anti-cellulite agent; to prevent or treat skin stretch marks; or as depigmenting agent.
37 . A method according to claim 35 for preventing or delaying premature skin ageing.
38 . A method according to claim 37 for preventing or delaying photo-induced premature skin ageing.
39 . A method according to claim 35 for preventing, reducing or treating wrinkles, lines or microrelief deterioration, or a combination of these indications.
40 . A method according to claim 37 for reinforcing the mechanical properties of the skin and mucosae, or reinforcing or restoring skin elasticity or firmness, or a combination of these indication.
41 . A method according to claim 40 for combating withered, flabby, slackened, sagging or thinned skin, or a combination of these conditions.
42 . A method according to claim 35 for promoting healing.
43 . A method according to claim 35 for preventing or treating pathologies or conditions selected from the group formed by surface scarring, fragile lips and cheilitis, stretch marks, skin after stings and bites, skin abrasions, spots or skin scabs, and fragile and sensitive skin, or a combination of these indications.
44 . A method for cosmetic care or cosmetic treatment for the skin, skin appendages, mucosae, or a combination thereof, to improve the condition or appearance thereof, comprising administering an extract according to claim 22 via oral or topical route.
45 . A method for cosmetic care according to claim 44 for improving firmness, elasticity or tonicity of the skin.
46 . A method for cosmetic treatment according to claim 44 for dry skin with feeling of tightness.
47 . A method for cosmetic treatment according to claim 44 for remodeling the silhouette, limiting “orange peel” effect.Cited by (0)
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