US2016250274A1PendingUtilityA1

Protective Effects of Oil Palm Composition on Alzheimer's Disease

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Assignee: MALAYSIAN PALM OIL BOARDPriority: Oct 11, 2013Filed: Oct 10, 2014Published: Sep 1, 2016
Est. expiryOct 11, 2033(~7.2 yrs left)· nominal 20-yr term from priority
Inventors:Robert P. WeinbergChokyun RhaAnthony J. SinskeyYew Ai TanRavigadevi Sambanthamurthi
A61P 25/28A23D 9/007A23L 33/105A23L 33/115A61K 2236/15A61K 36/889
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Claims

Abstract

Present invention discloses an oil palm composition for use in prevention or treatment of Alzheimer's disease. The composition is useful in impeding formation of neurotoxic peptide. Present invention can be used in preparation of a medicament in a therapeutic effective amount for prevention or treatment of Alzheimer's disease and diseases related thereto.

Claims

exact text as granted — not AI-modified
1 . A composition comprising vegetation liquor, wherein said composition is useful in preventing or treatment of Alzheimer's disease and diseases related thereto. 
     
     
         2 . The composition as claimed in  claim 1  wherein said vegetation liquor is oil palm phenolics. 
     
     
         3 . The composition as claimed in  claim 1  is useful in impeding aggregation of β-amyloid. 
     
     
         4 . The composition as claimed in  claim 2  wherein said β-amyloid aggregation will lead to formation of neurotoxic Aβ-dimer. 
     
     
         5 . The composition as claimed in  claim 1  is useful in impeding polymerization of β-amyloid. 
     
     
         6 . The composition as claimed in  claim 1  is useful in impeding folding of β-pleated sheet secondary structure in β-amyloid peptide. 
     
     
         7 . The composition as claimed in  claim 1  is useful in inhibiting kinetic accumulation of the β-pleated sheet amyloid peptide. 
     
     
         8 . The composition as claimed in  claim 1  can be used in preparation of a medicament in a therapeutic effective amount. 
     
     
         9 . The composition as claimed in  claim 1  may be administered orally, conventional treatment forms, pharmaceutical formulations, nutritional supplement or as nutraceutical supplement. 
     
     
         10 . Use of therapeutically effective amount of a composition as claimed in  claim 1 , in the preparation of a medicament for prevention or treatment of Alzheimer's disease and diseases related thereto in an individual in need thereof.

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