Methods for the Compensation of Imaging Technique In The Processing of Radiographic Images

Abstract

The present invention relates to methods and devices for analyzing x-ray images. In particular, devices, methods and algorithms are provided that allow for the accurate and reliable evaluation of bone structure and macro-anatomical parameters from x-ray images.

1 . A method to derive information regarding one or more bone parameters from an image comprising:
 (a) obtaining image data of bone from a subject;   (b) defining a first region of interest from the image data;   (c) defining a second region of interest from the image data, wherein the first and second regions of interest overlap;   (d) analyzing information in the first region of interest to determine at least a first value for a bone parameter, the bone parameter selected from the group consisting of bone microarchitecture, bone macroanatomy, biomechanical parameters and combinations thereof;   (e) analyzing information in the second region of interest to determine at least a second value for the bone parameter; and   (f) generating a set of data at least in part from the first and second values.   
     
     
         2 . The method of  claim 1 , further comprising creating a parameter map based at least in part on the first and second values for the bone parameter. 
     
     
         3 . The method of  claim 2 , comprising generating multiple parameter maps and generating a composite parameter map from the multiple parameter maps.