Gas dispenser for dispensing accurate doses of therapeutic gas from a reservoir containing highly compressed therapeutic gas

Abstract

Described here are devices for intranasally delivering therapeutic gases to a patient. The devices may include a measurement chamber, a combination of pressure regulators and a sequencing mechanism that controls valves associated with the pressure regulators. When implemented in a hand-held dispenser, the hand-held dispenser may reliably deliver consistent doses of gas regardless of the unknown state and pressure of the therapeutic gas in the measurement chamber.

1 . A device for dispensing a therapeutic gas to a patient comprising:
 a compressed gas cylinder,   a first valve and a second valve,   a first pressure regulator and a second pressure regulator,   a measurement chamber that has a defined volume of therapeutic gas at a predetermined pressure set by the first pressure regulator, and   a sequencing mechanism that is coupled to the first valve and the second valve, wherein the sequence mechanism alternately opens and closes the first valve and second valve,   wherein the compressed gas cylinder is coupled to input of the first valve, and output of the first valve is coupled to input on the first pressure regulator, and output of the first pressure regulator is coupled to input of the second pressure regulator and to the measurement chamber,   wherein output of the second pressure regulator is coupled to input of the second valve and output of the second valve is coupled to the patient,   wherein the therapeutic gas passes from the compressed gas cylinder through the first pressure regulator to the measurement chamber, then the therapeutic gas passes from the measurement chamber through the second pressure regulator to provide the patient a constant volume of therapeutic gas.   
     
     
         2 . The device as in  claim 1 , further comprising an orifice to control rate of gas flow, wherein the output of the second valve is coupled to one end of the orifice and another end of the orifice is coupled to the patient. 
     
     
         3 . The device as in  claim 1 , wherein the sequence mechanism is either a mechanical or an electronic apparatus. 
     
     
         4 . The device as in  claim 1 , wherein the therapeutic gas is carbon dioxide. 
     
     
         5 . The device as in  claim 1 , wherein the measurement chamber stores a volume of therapeutic gas at a controlled pressure of approximately 200 psi. 
     
     
         6 . The device as in  claim 1 , wherein the patient receives a constant flow rate of gas of approximately 0.5 standard liters per minute. 
     
     
         7 . The device as in  claim 1 , wherein the patient receives the therapeutic gas at a controlled pressure of approximately 1 atmosphere. 
     
     
         8 . The device as in  claim 1 , wherein the device is utilized in a hand-held dispenser. 
     
     
         9 . A method for delivering intranasally a therapeutic gas to a patient comprising the steps of:
 obtaining the device according to  claim 1 ,   activating the sequence mechanism to open the first valve and close the second valve to allow the therapeutic gas to flow from the compressed gas cylinder to the measurement chamber,   activating the sequence mechanism to close the first valve and open the second valve to allow the therapeutic gas to flow from the measurement chamber to the patient,   wherein the patient receives the therapeutic gas at a constant flow rate and pressure.