Alkoxysilane derivatives of n-acyl amino acids, n-acyl dipeptides, and n-acyl tripeptides, and particles and stable oil-in-water formulations using the same

Abstract

Hydrophilic N-acylamino acid, N-acyl dipeptide, and N-acyl tripeptide substituted silanes are prepared which can be utilized as reactive surface treatments for particles of pigments, minerals, and fillers. These treated particles form stable dispersions in the aqueous phase of oil-in-water mixtures that are suitable for cosmetic applications. The treated particles may also be used in pressed powder and color cosmetic formulations.

1 . A hydrophilic alkoxysilane derivative of an N-acyl dipeptide or N-acyl tripeptide, wherein the acyl group is acetyl. 
     
     
         2 . The hydrophilic alkoxysilane derivative according to  claim 1 , wherein the alkoxy group is selected from the group consisting of methoxy and ethoxy. 
     
     
         3 . The hydrophilic alkoxysilane derivative according to  claim 1 , wherein the derivative is a propyltrialkoxysilane derivative. 
     
     
         4 . The hydrophilic alkoxysilane derivative according to  claim 1 , wherein the derivative is (N-acetylglycylpropyl)triethoxysilane. 
     
     
         5 . The hydrophilic alkoxysilane derivative according to  claim 1 , wherein the derivative is (N-acetylglycinamidepropyl) trimethoxysilane. 
     
     
         6 . The hydrophilic alkoxysilane derivative according to  claim 1 , wherein the derivative is (N-acetylleucinamidepropyl)triethoxysilane. 
     
     
         7 . (N-acetylhydroxyprolyl)propyltriethoxysilane. 
     
     
         8 . The hydrophilic alkoxysilane derivative according to  claim 1 , comprising an amino acid residue selected from glycine and hydroxyproline.