Sealant storage, preparation, and delivery systems and related methods

Abstract

A bioadhesive sealant storage and preparation system may comprise a plurality of containers and an adapter. The plurality of containers may comprise a first container having a first bioadhesive sealant component therein, and a second container having a second bioadhesive sealant component therein. The adapter may comprise a manifold comprising a plurality of channels formed therein, an inlet region sized and configured to receive the plurality of containers and facilitate fluid communication between each container of the plurality of containers and a respective channel of the plurality of channels, and an outlet region sized and configured to receive a syringe and provide fluid communication between the syringe and the plurality of channels.

1 - 16 . (canceled) 
     
     
         17 . A method of preparing a bioadhesive sealant, the method comprising:
 applying a force to a plurality of containers located at an inlet of an adapter, the plurality of containers comprising a first container having a first bioadhesive sealant component therein and a second container having a second bioadhesive sealant component therein, to facilitate fluid communication between the plurality of containers and a manifold of the adapter;   substantially simultaneously drawing the first bioadhesive sealant component and the second bioadhesive sealant component into a syringe coupled to an outlet region of the adapter through the manifold.   
     
     
         18 . The method of  claim 17 , further comprising drawing the first bioadhesive sealant component into the second container. 
     
     
         19 . The method of  claim 17 , further comprising moving a movable barrier located between the plurality of containers and a manifold of the adapter prior to applying the force to the plurality of containers. 
     
     
         20 . The method of  claim 17 , further comprising maintaining the plurality of containers in a sealed region of a pouch separate from a sterile region wherein the syringe is located. 
     
     
         21 . A method of delivering sealant to a tissue puncture, the method comprising:
 applying a force to a plurality of containers located at an inlet of an adapter, the plurality of containers comprising a first container having a first bioadhesive sealant component therein and a second container having a second bioadhesive sealant component therein, to facilitate fluid communication between the plurality of containers and a manifold of the adapter;   substantially simultaneously drawing the first bioadhesive sealant component and the second bioadhesive sealant component into a syringe coupled to an outlet region of the adapter through the manifold;   uncoupling the syringe from the adapter;   coupling the syringe to a proximal end of a delivery tube;   inserting a distal end of the delivery tube into a tissue puncture;   delivering a bioadhesive sealant from the syringe into the proximal end of the delivery tube and conveying the bioadhesive sealant through the delivery tube to the distal end of the delivery tube and into the tissue puncture.