Multidrug-Resistant Gram-Positive Bacteria Antibacterial Agent and Topical Agent

Abstract

To provide a multidrug-resistant Gram positive bacteria antibacterial agent containing as an active ingredient a novel component to which multidrug-resistant bacteria are not resistant, and an external agent containing the same. The multidrug resistant Gram-positive bacteria antibacterial agent according to the present invention contains an amphipathic compound having an HLB value of greater than 9.5 and 20 or less and an acyl group as an active ingredient. The external agent according to the present invention contains the multidrug resistant Gram-positive bacteria antibacterial agent.

1 . A multidrug resistant Gram-positive bacteria antibacterial agent containing an amphipathic compound having an HLB value of greater than 9.5 and 20 or less and an acyl group as an active ingredient, the amphipathic compound having an acyl group being monoacyl glycerophospholipid and/or sucrose fatty acid ester. 
     
     
         2 . The multidrug resistant Gram-positive bacteria antibacterial agent according to  claim 1 ,
 wherein the monoacyl glycerophospholipid includes lyso phosphatidylcholine.   
     
     
         3 . The multidrug resistant Gram-positive bacteria antibacterial agent according to  claim 2 ,
 wherein the monoacyl glycerophospholipid includes those derived from egg yolk.   
     
     
         4 . The multidrug resistant Gram-positive bacteria antibacterial agent according to  claim 1 ,
 in which the active ingredient is contained at a concentration of 300 ppm or more.   
     
     
         5 . An external agent containing the multidrug resistant Gram-positive bacteria antibacterial agent according to  claim 1 . 
     
     
         6 . The multidrug resistant Gram-positive bacteria antibacterial agent according to  claim 2 ,
 in which the active ingredient is contained at a concentration of 300 ppm or more.   
     
     
         7 . The multidrug resistant Gram-positive bacteria antibacterial agent according to  claim 3 ,
 in which the active ingredient is contained at a concentration of 300 ppm or more.   
     
     
         8 . An external agent containing the multidrug resistant Gram-positive bacteria antibacterial agent according to  claim 2 . 
     
     
         9 . An external agent containing the multidrug resistant Gram-positive bacteria antibacterial agent according to  claim 3 . 
     
     
         10 . An external agent containing the multidrug resistant Gram-positive bacteria antibacterial agent according to  claim 4 .