Methods of radiometrically determining an extreme temperature during a treatment procedure

Abstract

According to some embodiments, systems for energy delivery to targeted tissue comprise a catheter with an ablation member, a radiometer configured to detect temperature data from the targeted tissue, a processor configured to determine a calculated temperature (e.g., an extreme temperature, such as a peak or trough temperature) within the tissue by applying at least one factor to the temperature data detected by the radiometer, the processor configured to compare the calculated temperature to a setpoint and an energy source configured to energize the ablation member and to regulate delivery of ablative energy to the targeted tissue of the subject based at least in part on the comparison. In some embodiments, the factor depends on at least one characteristic of the targeted tissue. Information regarding a tissue characteristic can be provided using information from an imaging set (e.g., intracardiac echo) or an electrical signal of the subject (e.g., electrocardiogram).

1 - 10 . (canceled) 
     
     
         11 . A system for energy delivery to a targeted tissue of a subject, comprising.
 a processor configured to determine a calculated temperature within the targeted tissue by adjusting temperature data received by a radiometer using at least one factor; and   an ablation energy source configured to energize an ablation member to deliver energy to the targeted tissue of the subject based on, at least in part, the calculated temperature.   
     
     
         12 . The system of  claim 11 , wherein the calculated temperature relates to an extreme temperature within the targeted tissue. 
     
     
         13 . The system of  claim 11 , further comprising an input device configured to receive a setpoint, the setpoint comprising a target ablation temperature of the targeted tissue or a set curve, wherein the energy source is configured to regulate delivery of energy to targeted tissue by comparing the calculated temperature to the setpoint. 
     
     
         14 . The system of  claim 11 , wherein the at least one factor comprises an estimation factor, the estimation factor depending on, at least in part, at least one characteristic of the targeted tissue. 
     
     
         15 . The system of  claim 14 , wherein the at least one characteristic of the targeted tissue comprises at least one of a thickness of the targeted tissue, a type of the targeted tissue, a location of the targeted tissue and a density of the targeted tissue and a characteristic of the subject being treated. 
     
     
         16 . The system of  claim 12 , wherein the ablation member is configured to heat the targeted tissue when energized and the extreme temperature comprises a peak temperature within the targeted tissue, or wherein the ablation member is configured to cool the targeted tissue when energized and the extreme temperature comprises a trough temperature within the targeted tissue. 
     
     
         17 . The system of  claim 14 , wherein information related to the at least one characteristic of the targeted tissue is provided using at least one of imaging data and electrical signal data of the subject or is provided manually by a user. 
     
     
         18 . A system for energy delivery to a targeted tissue of a subject, comprising:
 a processor configured to determine a calculated temperature within the targeted tissue by adjusting temperature data received by a radiometer using at least one factor; and   an energy source configured to deliver energy to an energy delivery member to deliver energy to the targeted tissue of the subject based on, at least in part, the calculated temperature.   
     
     
         19 . The system of  claim 18 , wherein the at least one factor comprises an estimation factor, the estimation factor depending on, at least in part, at least one characteristic of the targeted tissue. 
     
     
         20 . The system of  claim 18 , wherein the calculated temperature relates to an extreme temperature within the targeted tissue, the extreme temperature comprising a peak temperature or a trough temperature.