Anti-microbial composition comprising cannabinoids

Abstract

This invention discloses anti-bacterial and anti-fungal compositions in spray form, in cream form, in liquid form, and in powder form. The anti-bacterial and anti-fungal compositions comprise cannabinoids, specifically cannabidiol, cannabigerol, tetrahydrocannabinol, tetracannabidivarin, and/or cannabidivarin for anti-bacterial and anti-fungal activities. The anti-bacterial and anti-fungal compositions may be used to treat toe nail fungus, MRSA infection, herpes virus infection, tinea pedis, burn wound infections, sun burns, diabetic infections, eczema, impetigo, dermatophytosis, psoriasis, itchy skin, atopic dermatitis, dandruff, and general topical infections.

1 . An anti-microbial composition in cream form comprising:
 at least one cannabinoid at 2% to 5% by weight of the total composition;   at least one alcoholic solvent at 20% to 40% by weight of the total composition;   a humectant at 1% to 5% by weight of the total composition;   an emulsifier at 2% to 15% by weight of the total composition; and   water at 30% to 50% by weight of the total composition.   
     
     
         2 . The anti-microbial composition of  claim 1 , further comprising a binding agent selected from the group consisting of alginic acid, ammonium alginate, calcium caseinate, calcium sulfate hydrate, polyvinyl acetate, polyacrylic acid, polyisobutylene, potassium alginate, propylene glycol alginate, and polyvinylpyrrolidone. 
     
     
         3 . The anti-microbial composition of  claim 2 , wherein the binding agent is present at 5% to 20% by weight of the total composition. 
     
     
         4 . The anti-microbial composition of  claim 2 , further comprising a skin conditioning agent selected from the group consisting of amodimethicone, alkyl benzoate, caprylyl glycol, cetyl palminate, cyclo-dimethicone, dimethicone 500, dimethicone satin, ethylhexyl glycerin, iso-dimethicone copolymer, isododecane, isoeicosane, isolanolin, lanolin alcohol, octyldodecanol, PEG-8 dimethicone, and polyamide 3. 
     
     
         5 . The anti-microbial composition of  claim 4 , wherein the skin conditioning agent is present at 0.1% to 2% by weight of the total composition. 
     
     
         6 . The anti-microbial composition of  claim 5 , further comprising a fragrance. 
     
     
         7 . An anti-microbial spray comprising:
 at least one cannabinoid at 2% to 5% by weight of the total composition selected from the group consisting of cannabidiol, cannabigerol, tetrahydrocannabinol, cannabidivarin, and tetrahydrocannabivarin;   a humectant at 1% to 5% by weight of the total composition selected from the group consisting of glycerin, hyaluronic acid, lacto-ceramide, hydrolyzed keratin protein, and hydrolyzed collagen protein;   an emulsifier at 2% to 15% by weight of the total composition selected from the group consisting of PEG 40 hydrogenated castor oil, disodium PEG-4-cocoamido MIPA sulfosuccinate, lauryl glucoside, methyl gluceth-10, and sodium lauroamphoacetate;   at least one alcohol at 30% to 45% by weight of the total composition selected from the group consisting of ethanol and isopropyl alcohol; and   water at 30% to 50% by weight of the total composition.   
     
     
         8 . The anti-microbial spray of  claim 7 , further comprising a chelating agent present at 0.05% to 0.5% by weight of the total composition selected from the group consisting of disodium gluconate, disodium EDTA, tetrasodium EDTA, and tetrasodium glutamate diacetate. 
     
     
         9 . The anti-microbial spray of  claim 8 , further comprising a skin conditioning agent present at 0.1% to 2% by weight of the total composition selected from the group consisting of amodimethicone, alkyl benzoate, caprylyl glycol, cetyl palminate, cyclo-dimethicone, dimethicone 500, dimethicone satin, ethylhexyl glycerin, iso-dimethicone copolymer, isododecane, isoeicosane, isolanolin, lanolin alcohol, octyldodecanol, PEG-8 dimethicone, and polyamide 3. 
     
     
         10 . The anti-microbial spray of  claim 9 , further comprising a fragrance. 
     
     
         11 . An anti-microbial liquid comprising:
 at least one cannabinoid at 5% to 10% by weight of the total composition selected from the group consisting of cannabidiol, cannabigerol, tetrahydrocannabinol, cannabidivarin, and tetrahydrocannabivarin;   a surfactant at 3% to 10% by weight of the total composition selected from the group consisting of sodium lauryl sulfate, ammonium lauryl sulfate, sodium laureth sulfate, and sodium myreth sulfate;   at least one alcohol at 30% to 45% by weight of the total composition selected from the group consisting of ethanol or isopropyl alcohol; and   water at 35% to 55% by weight of the total composition.   
     
     
         12 . An anti-microbial powder comprising:
 at least one cannabinoid at 5% to 10% by weight of the total composition selected from the group consisting of cannabidiol, cannabigerol, tetrahydrocannabinol, cannabidivarin, and tetrahydrocannabivarin;   at least one preservative at 0.2% to 1.5% by weight of the total composition selected from the group consisting of butylhydroxytoluene, phenoxyethanol, paraben, and potassium sorbate;   at least one emollient at 3% to 20% by weight of the total composition selected from the group consisting of dimethyl polysiloxilane, isopropyl myristate, amodimethicone, cetyl palmitate, cyclomethicone, dimethicone 500, and isododecane; and   a powder comprising talc and hydrated silica at 20% to 90% by weight of the total composition.   
     
     
         13 . The anti-microbial powder of  claim 12 , further comprising:
 at least one alcohol at 20% to 80% by weight of the total composition selected from the group consisting of ethanol and isopropyl alcohol; and   at least one propellant solvent at 20% to 70% by weight of the total composition selected from the group consisting of butane, isobutane, propane, pentane, and dimethyl ether.   
     
     
         14 . The anti-microbial powder of  claim 13 , wherein the powder is packaged in an aerosol can. 
     
     
         15 . A method to make an anti-microbial composition comprising the steps of:
 dissolving at least one solid cannabinoid into an alcohol to form a solution;   adding at least one of an emulsifier, a humectant, a chelating agent, a binding agent, or a skin conditioning agent to the solution;   stirring the solution;   adding water to the solution; and   stirring the solution.   
     
     
         16 . The method of  claim 15 , further comprising the steps of:
 adding a fragrance to the solution; and   adjusting the solution's pH to 6.   
     
     
         17 . A method to make an anti-microbial powder comprising the steps of:
 dissolving at least one solid cannabinoid into an alcohol to form a solution;   adding at least one emollient and at least one preservative into the solution from the first step;   adding the solution from the second step into a powder comprising talc and hydrated silica to form a powder;   mixing the powder mixture in a shear mixer;   adding the powder into an aerosol can; and   adding at least one propellant selected from the group consisting of butane, isobutane, propane, pentane, and dimethyl ether.   
     
     
         18 . The method of  claim 17 , further comprising the step of removing the alcohol by vacuum. 
     
     
         19 . A method to disinfect a surface comprising the steps of:
 applying an effective amount of a composition according to  claim 1  to a surface; and   leaving the composition on the surface for at least 3 minutes,   wherein the surface is either mammal skin or non-living surfaces.   
     
     
         20 . A method to treat an infection on human skin comprising the steps of:
 applying a therapeutically effective amount of a composition according to  claim 1  to the skin; and   leaving the composition on the skin for at least 3 minutes,   wherein the infection is selected from the group consisting of toe nail fungus, MRSA infection, herpes virus infection, tinea pedis, burn wound infections, sun burns, diabetic infections, eczema, impetigo, dermatophytosis, psoriasis, itchy skin, atopic dermatitis, dandruff, and general topical infections.   
     
     
         21 . The anti-microbial composition of  claim 1 , wherein:
 the at least one cannabinoid is selected from the group consisting of cannabidiol, cannabigerol, tetrahydrocannabinol, cannabidivarin, and tetrahydrocannabivarin;   the at least one alcoholic solvent is selected from the group consisting of ethanol and isopropyl alcohol;   the humectant is selected from the group consisting of glycerin, hyaluronic acid, lacto-ceramide, hydrolyzed keratin protein, and hydrolyzed collagen protein, and   the emulsifier is selected from the group consisting of PEG 40 hydrogenated castor oil, disodium PEG-4-cocoamido MIPA sulfosuccinate, lauryl glucoside, and sodium lauroamphoacetate.