US2017000811A1PendingUtilityA1

Prebiotic oligosaccharides

Assignee: UNIV CALIFORNIAPriority: Mar 13, 2009Filed: Jul 22, 2016Published: Jan 5, 2017
Est. expiryMar 13, 2029(~2.6 yrs left)· nominal 20-yr term from priority
A61P 35/00A61K 2035/115A61P 1/14C12Y 302/01108A23L 33/135A61P 1/06A23V 2002/00A23L 33/40A61K 31/702A61K 35/745A23L 33/125A61K 9/0095A23L 5/00A61K 38/47A23L 7/00A61P 1/04A61P 1/10A61P 1/00A23L 33/21A23L 29/30A61P 1/12
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Claims

Abstract

The present invention provides galacto-oligosaccharide compositions that preferentially stimulate growth of specific Bifidobacterium species and subspecies.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method for stimulating beneficial  Bifidobacterium  microflora in an animal, the method comprising,
 administering a sufficient amount of the composition of galacto-oligosaccharides, wherein at least 45% of the galacto-oligosaccharides by weight are tetra or penta galacto-oligosaccharides or wherein at least 25% of the galacto-oligosaccharides by weight are tetra galacto-oligosaccharides, to the animal to stimulate colonization of the gut of the animal by at least one beneficial  Bifidobacterium  strain.   
     
     
         2 . The method of  claim 1 , wherein the composition further comprises  Bifidobacterium breve  or  Bifidobacterium longum  bv.  infantis.    
     
     
         3 . The method of  claim 1 , wherein the composition has less than 20% by weight of dimeric galacto-oligosaccharides, based on weight of the total oligosaccharides. 
     
     
         4 . The method of  claim 1 , wherein the composition has less than 10% by weight of dimeric galacto-oligosaccharides, based on weight of the total oligosaccharides. 
     
     
         5 . The method of  claim 1 , wherein the composition has less than 5% by weight of monomeric sugars based on total sugar and oligosaccharide solids. 
     
     
         6 . The method of  claim 1 , wherein the composition has less than 5% by weight of lactose, based on weight of the total oligosaccharides. 
     
     
         7 . The method of  claim 1 , wherein the composition comprises a lactase enzyme. 
     
     
         8 . The method of  claim 1 , wherein the composition is a food product or dietary supplement product. 
     
     
         9 . The method of  claim 1 , wherein the food product is selected from the group consisting of an infant formula, a follow-on formula, and a toddler beverage. 
     
     
         10 . The method of  claim 1 , wherein less than 10% of the galacto-oligosaccharides by weight have a degree of polymerization of 6 or greater. 
     
     
         11 . The method of  claim 1 , wherein less than 10% of the galacto-oligosaccharides by weight are trimeric galacto-oligosaccharides. 
     
     
         12 . The method of  claim 1 , wherein more than 30% of the galacto-oligosaccharides by weight are trimeric galacto-oligosaccharides. 
     
     
         13 . The method of  claim 1 , wherein at least 50% of the galacto-oligosaccharides by weight are tetra or penta galacto-oligosaccharides. 
     
     
         14 . The method of  claim 13 , wherein less than 10% of the galacto-oligosaccharides by weight are trimeric galacto-oligosaccharides. 
     
     
         15 . The method of  claim 14 , wherein the composition further comprises  Bifidobacterium breve  or  Bifidobacterium longum  bv.  infantis.    
     
     
         16 . The method of  claim 1 , wherein at least 30% of the galacto-oligosaccharides by weight are tetra galacto-oligosaccharides. 
     
     
         17 . The method of  claim 16 , wherein less than 10% of the galacto-oligosaccharides by weight are trimeric galacto-oligosaccharides. 
     
     
         18 . The method of  claim 17 , wherein the composition further comprises  Bifidobacterium breve  or  Bifidobacterium longum  bv.  infantis.    
     
     
         19 . The method of  claim 1 , wherein the animal is a human.

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