US2017000811A1PendingUtilityA1
Prebiotic oligosaccharides
Est. expiryMar 13, 2029(~2.6 yrs left)· nominal 20-yr term from priority
Inventors:Mariana BarbozaJ. Bruce GermanCarlito B. LebrillaDavid A. MillsSamara Freeman-SharkeyWilliam King
A61P 35/00A61K 2035/115A61P 1/14C12Y 302/01108A23L 33/135A61P 1/06A23V 2002/00A23L 33/40A61K 31/702A61K 35/745A23L 33/125A61K 9/0095A23L 5/00A61K 38/47A23L 7/00A61P 1/04A61P 1/10A61P 1/00A23L 33/21A23L 29/30A61P 1/12
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Claims
Abstract
The present invention provides galacto-oligosaccharide compositions that preferentially stimulate growth of specific Bifidobacterium species and subspecies.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1 . A method for stimulating beneficial Bifidobacterium microflora in an animal, the method comprising,
administering a sufficient amount of the composition of galacto-oligosaccharides, wherein at least 45% of the galacto-oligosaccharides by weight are tetra or penta galacto-oligosaccharides or wherein at least 25% of the galacto-oligosaccharides by weight are tetra galacto-oligosaccharides, to the animal to stimulate colonization of the gut of the animal by at least one beneficial Bifidobacterium strain.
2 . The method of claim 1 , wherein the composition further comprises Bifidobacterium breve or Bifidobacterium longum bv. infantis.
3 . The method of claim 1 , wherein the composition has less than 20% by weight of dimeric galacto-oligosaccharides, based on weight of the total oligosaccharides.
4 . The method of claim 1 , wherein the composition has less than 10% by weight of dimeric galacto-oligosaccharides, based on weight of the total oligosaccharides.
5 . The method of claim 1 , wherein the composition has less than 5% by weight of monomeric sugars based on total sugar and oligosaccharide solids.
6 . The method of claim 1 , wherein the composition has less than 5% by weight of lactose, based on weight of the total oligosaccharides.
7 . The method of claim 1 , wherein the composition comprises a lactase enzyme.
8 . The method of claim 1 , wherein the composition is a food product or dietary supplement product.
9 . The method of claim 1 , wherein the food product is selected from the group consisting of an infant formula, a follow-on formula, and a toddler beverage.
10 . The method of claim 1 , wherein less than 10% of the galacto-oligosaccharides by weight have a degree of polymerization of 6 or greater.
11 . The method of claim 1 , wherein less than 10% of the galacto-oligosaccharides by weight are trimeric galacto-oligosaccharides.
12 . The method of claim 1 , wherein more than 30% of the galacto-oligosaccharides by weight are trimeric galacto-oligosaccharides.
13 . The method of claim 1 , wherein at least 50% of the galacto-oligosaccharides by weight are tetra or penta galacto-oligosaccharides.
14 . The method of claim 13 , wherein less than 10% of the galacto-oligosaccharides by weight are trimeric galacto-oligosaccharides.
15 . The method of claim 14 , wherein the composition further comprises Bifidobacterium breve or Bifidobacterium longum bv. infantis.
16 . The method of claim 1 , wherein at least 30% of the galacto-oligosaccharides by weight are tetra galacto-oligosaccharides.
17 . The method of claim 16 , wherein less than 10% of the galacto-oligosaccharides by weight are trimeric galacto-oligosaccharides.
18 . The method of claim 17 , wherein the composition further comprises Bifidobacterium breve or Bifidobacterium longum bv. infantis.
19 . The method of claim 1 , wherein the animal is a human.Join the waitlist — get patent alerts
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