US2017007403A1PendingUtilityA1

Implantable device for the locationally accurate delivery and administration of substances into the pericardium or onto the surface of the heart

41
Assignee: AdjuCor GmbHPriority: Jul 8, 2015Filed: Jul 8, 2015Published: Jan 12, 2017
Est. expiryJul 8, 2035(~9 yrs left)· nominal 20-yr term from priority
Inventors:Stephen Manuel WildhirtAndreas MaierKei Wieland MüllerBjorn Hofmann
A61L 2430/20A61L 2300/64A61L 31/146A61F 2240/001A61L 2300/60A61F 2002/2484A61L 31/148A61M 5/14276A61M 2205/04A61L 31/16A61F 2230/0067A61L 31/005A61F 2250/0068A61M 2205/05A61F 2/2481A61M 5/1723A61M 5/14A61M 2210/125A61M 2210/122
41
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The present invention relates to a device for the administration of substances onto the epicardial surface of the heart. The device comprises a frame structure which is able to assume shaping, positioning, guiding and stabilizing functions. The frame structure may contain at least one sleeve. The device comprises a substance carrier which is able to accommodate the substance to be administered.

Claims

exact text as granted — not AI-modified
1 . Device for the administration of a substance to a surface of the heart comprising:
 a frame structure,   a sleeve,   a substance carrier and   a substance to be administered.   
     
     
         2 . Device according to  claim 1 , further comprising an expandable unit. 
     
     
         3 . Device according to  claim 2 , wherein the expandable unit is mounted on the sleeve. 
     
     
         4 . Device according to  claim 2 , wherein the expandable unit is part of the sleeve. 
     
     
         5 . Device according to one of  claims 2 , wherein the substance carrier is mounted on the expandable unit. 
     
     
         6 . Device according to  claim 1 , wherein the substance carrier is mounted on the sleeve. 
     
     
         7 . Device according to  claim 1 , wherein the substance carrier is a pocket. 
     
     
         8 . Device according to  claim 7 , wherein the substance to be administered is inserted into the pocket. 
     
     
         9 . Device according to  claim 7 , wherein the substance to be administered is inserted into the pocket on a carrier. 
     
     
         10 . Device according to  claim 7 , wherein the pocket has a removable area on the surface of the pocket facing the heart. 
     
     
         11 . Device according to  claim 10 , wherein the removable area may be removed from outside the body after implantation of the device. 
     
     
         12 . Device according to  claim 10 , wherein the removable area is at least partially biodegradable. 
     
     
         13 . Device according to  claim 7 , wherein the pocket comprises a permeable area. 
     
     
         14 . Device according to  claim 1 , wherein the substance carrier has a delivery line. 
     
     
         15 . Device according to  claim 1 , wherein the substance carrier comprises a spongy or porous structure. 
     
     
         16 . Device according to  claim 1 , wherein the sleeve is affixed to the frame structure. 
     
     
         17 . Device according to  claim 1 , wherein the device may be implanted minimally invasively. 
     
     
         18 . Device according to  claim 1 , wherein the frame structure is made out of wire, in particular out of a wire comprising a shape memory alloy. 
     
     
         19 . Device according to  claim 1 , wherein the substance to be administered is a pharmaceutical active agent. 
     
     
         20 . Device according to  claim 1 , wherein the substance to be administered comprises cells. 
     
     
         21 . Device according to  claim 1  further comprising a supply unit. 
     
     
         22 . Device according to  claim 21 , wherein the supply unit comprises a substance reservoir. 
     
     
         23 . Device for implanting the device according to  claim 1 , wherein the device for implanting comprises a tubular delivery system. 
     
     
         24 . Device for implanting according to  claim 23 , wherein the tubular delivery system has a distal end face which is slanted. 
     
     
         25 . Device for explanting the device according to one of the  claims 1 , wherein the device for explanting comprises a cylindrical tube. 
     
     
         26 . Device for explanting according to  claim 25 , wherein the cylindrical tube comprises a radial widening at the distal end. 
     
     
         27 . Method for producing a device for the administration of a substance onto a surface of the heart comprising the following steps:
 Provision of a frame structure;   Mounting of a sleeve on the frame structure;   Mounting of a substance carrier; and   Charging of the substance carrier with a substance to be administered.   
     
     
         28 . Method according to  claim 27 , wherein the substance carrier is mounted on the sleeve. 
     
     
         29 . Method according to  claim 27  further comprising an expandable unit. 
     
     
         30 . Method according to  claim 29 , wherein the substance carrier is mounted on the expandable unit. 
     
     
         31 . Method for the administration of a substance to a surface of the heart comprising:
 inserting a device for the administration of a substance to a surface of the heart comprising:
 a frame structure, 
 a sleeve, 
 a substance carrier and 
 a substance to be administered. 
   
     
     
         32 . The method of  claim 31  wherein inserting the device comprises:
 inserting a delivery device into the body and into the pericardium; and 
 inserting the device for the administration of a substance to a surface of the heart into the body and into the pericardium via the delivery device.

Cited by (0)

No later patents cite this yet.

References (0)

No backward citations on record.