Method for reversing hair loss and the loss of cuticle growth and density by administering effective courses of granulocyte-colony stimulating factor

Abstract

The present invention provides a method for re-growing hair in patients with androgenic alopecia by administering effective consecutive courses of Granulocyte-Colony Stimulating Factor or derivatives. After the state of re-growth is obtained, the hair growth is maintained by administering periodic courses of Granulocyte-Colony Stimulating Factor or derivatives. The invention further provides a method for increasing cuticle growth and density using a similar administration of effective consecutive courses of Granulocyte-Colony Stimulating Factor or derivatives. The increased cuticle growth and density is maintained by administering periodic courses of Granulocyte-Colony Stimulating Factor or derivatives.

1 . A method for re-growing hair in a patient with hair loss by administering effective consecutive courses of Granulocyte-Colony Stimulating Factor, wherein said Granulocyte-Colony Stimulating Factor is selected from a group consisting of Granulocyte-Colony Stimulating Factor, its derivative, functionally similar biological or chemical compound or combination thereof. 
     
     
         2 . The method of  claim 1 , wherein the effective consecutive courses of Granulocyte-Colony Stimulating Factor to re-growth hair are two or more consecutive courses repeated about every 3 to 8 days, wherein said consecutive course administers a daily dose of Granulocyte-Colony Stimulating Factor for about 3 to 6 days. 
     
     
         3 . The method of  claim 2 , wherein said daily dose of Granulocyte-Colony Stimulating Factor administers a Granulocyte-Colony Stimulating Factor dose of about 0.1 micrograms to 100 micrograms per kg body weight per day of Granulocyte-Colony Stimulating Factor on each day. 
     
     
         4 . The method of  claim 2 , wherein said Granulocyte-Colony Stimulating Factor daily dose is administered selected from a group consisting of subcutaneous injection, transdermal patch, intravenously, and orally. 
     
     
         5 . The method of  claim 1 , further comprising providing intravenously adult stem cells to increase hair growth and density upon administration of the effective consecutive courses of Granulocyte-Colony Stimulating Factor to re-growth hair. 
     
     
         6 . The method of  claim 1 , further comprising maintaining hair growth by a periodic effective course of Granulocyte-Colony Stimulating Factor after said consecutive courses are completed, wherein said treatment maintains the hair growth. 
     
     
         7 . The method of  claim 6 , wherein said periodic effective course of Granulocyte-Colony Stimulating Factor to said maintain hair growth is a course of Granulocyte-Colony Stimulating Factor administered daily for about 3 to 6 days and said course is repeated every 2 to 18 weeks, wherein daily dose of Granulocyte-Colony Stimulating Factor is a dose of about 0.1 micrograms to 100 micrograms per kg body weight per day of Granulocyte-Colony Stimulating Factor on each day. 
     
     
         8 . The method of  claim 7 , wherein said administered is selected from a group consisting of subcutaneous injection, transdermal patch, intravenously, and orally. 
     
     
         9 . A method for increasing cuticle growth and density by administering effective consecutive courses of Granulocyte-Colony Stimulating Factor, wherein said Granulocyte-Colony Stimulating Factor is selected from a group consisting of Granulocyte-Colony Stimulating Factor, its derivative, functionally similar biological or chemical compound or combination thereof. 
     
     
         10 . The method of  claim 9 , wherein said effective consecutive courses of Granulocyte-Colony Stimulating Factor for increasing cuticle growth and density are two or more consecutive courses repeated about every 3 to 8 days, wherein said consecutive course administers a daily dose of Granulocyte-Colony Stimulating Factor for about 3 to 6 days. 
     
     
         11 . The method of  claim 10 , wherein said daily dose of Granulocyte-Colony Stimulating Factor administers a Granulocyte-Colony Stimulating Factor dose of about 0.1 micrograms to 100 micrograms per kg body weight per day of Granulocyte-Colony Stimulating Factor on each day. 
     
     
         12 . The method of  claim 9 , wherein said cuticle is a fingernail or a toe nail. 
     
     
         13 . The method of  claim 10 , wherein said Granulocyte-Colony Stimulating Factor daily dose is administered selected from a group consisting of subcutaneous injection, transdermal patch, intravenously, and orally. 
     
     
         14 . The method of  claim 9 , further comprising providing intravenously adult stem cells to increase hair growth and density upon administration of the effective consecutive courses of Granulocyte-Colony Stimulating Factor for increasing cuticle growth and density. 
     
     
         15 . The method of  claim 1 , further comprising maintaining cuticle growth and density by a periodic effective course of Granulocyte-Colony Stimulating Factor after said consecutive courses are completed, wherein said treatment maintains the cuticle growth and density. 
     
     
         16 . The method of  claim 15 , wherein said periodic effective course of Granulocyte-Colony Stimulating Factor to maintain cuticle growth and density is a course of Granulocyte-Colony Stimulating Factor administered daily for about 3 to 6 days and said course is repeated every 2 to 18 weeks, wherein daily dose of Granulocyte-Colony Stimulating Factor is a dose of about 0.1 micrograms to 100 micrograms per kg body weight per day of Granulocyte-Colony Stimulating Factor on each day. 
     
     
         17 . The method of  claim 15 , wherein said administered is selected from a group consisting of subcutaneous injection, transdermal patch, intravenously, and orally. 
     
     
         18 . A method to maintain hair growth by administering periodic effective courses of Granulocyte-Colony Stimulating Factor, wherein said Granulocyte-Colony Stimulating Factor is selected from a group consisting of Granulocyte-Colony Stimulating Factor, its derivative, functionally similar biological or chemical compound or combination thereof. 
     
     
         19 . A method for maintain cuticle growth and density by administering periodic effective courses of Granulocyte-Colony Stimulating Factor, wherein said Granulocyte-Colony Stimulating Factor is selected from a group consisting of Granulocyte-Colony Stimulating Factor, its derivative, functionally similar biological or chemical compound or combination thereof.