US2017056424A1PendingUtilityA1

Solid forms of tenofovir

Assignee: GILEAD SCIENCES INCPriority: Jan 15, 2014Filed: Oct 5, 2016Published: Mar 2, 2017
Est. expiryJan 15, 2034(~7.4 yrs left)· nominal 20-yr term from priority
A61P 31/18A61P 31/12A61P 31/20C07F 9/65616C07B 2200/13A61K 31/675
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Claims

Abstract

The present invention relates to solid forms of tenofovir and methods for preparation, use and isolation of such forms.

Claims

exact text as granted — not AI-modified
1 .- 21 . (canceled) 
     
     
         22 . A method for treating or preventing a viral infection in a human, comprising administering to the human a crystal form, Form I, of a compound: 
       
         
           
           
               
               
           
         
         which is characterized by a X-ray powder diffraction (XRPD) pattern comprising peaks expressed in degrees of two theta angle of 7.5±0.2, 15.0±0.2, 22.5±0.2 and 24.8±0.2 obtained using CuKα 1  X-ray. 
       
     
     
         23 . The method of  claim 22 , wherein the viral infection is human immunodeficiency virus (HIV). 
     
     
         24 . The method of  claim 22 , wherein the viral infection is hepatitis B virus (HBV).

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