Solid oral form of a medicinal preparation and a method for the production thereof

Abstract

A solid dosage form of an antibody-based medicinal preparation comprising an effective amount of a carrier treated with a dilution containing at least one antibody to a biologically active molecule.

1 .- 9 . (canceled) 
     
     
         10 . A solid dosage form for administration to a human subject, said dosage form comprising an effective amount of a pharmaceutically neutral carrier treated with a homeopathic dilution of an initial solution containing at least one antibody to a biologically-active molecule. 
     
     
         11 . The solid dosage form of  claim 10 , wherein said initial solution is obtained by i) generating an immune response to said biologically-active molecule in a host external to said human subject thereby generating said antibody in said host, and ii) isolating said generated antibody from said host. 
     
     
         12 . The solid dosage form of  claim 10 , wherein said biologically-active molecule is endogenous to said human subject. 
     
     
         13 . The solid dosage form of  claim 12 , wherein said biologically-active molecule plays a role in regulation of pathological syndrome for said human. 
     
     
         14 . The solid dosage form of  claim 12 , wherein said biologically-active molecule affects formation of pathological syndrome for said human. 
     
     
         15 . The solid dosage form of  claim 10 , wherein said homeopathic dilution is prepared by successive dilutions. 
     
     
         16 . The solid dosage form of  claim 15 , wherein said homeopathic dilution is prepared by combining said successive dilutions with external treatment. 
     
     
         17 . The solid dosage form of  claim 16 , wherein said external treatment is mechanical shaking, ultrasonic treatment, or electromagnetic field treatment. 
     
     
         18 . The solid dosage form of  claim 10 , wherein said carrier is lactose. 
     
     
         19 . The solid dosage form of  claim 18 , which is in the form of a tablet. 
     
     
         20 . The solid dosage form of  claim 19 , wherein said carrier comprises from 30% to 80% by weight with respect to total weight of said dosage form. 
     
     
         21 . The solid dosage form of  claim 20 , further comprising a binder and a lubricant. 
     
     
         22 . The solid dosage form of  claim 21 , wherein said lubricant comprises from 0.8% to 1.2% by weight with respect to total weight of said dosage form. 
     
     
         23 . The solid dosage form of  claim 21 , wherein said binder comprises from 10% to 15% by weight with respect to total weight of said dosage form. 
     
     
         24 .- 28 . (canceled) 
     
     
         29 . The solid oral dosage form of  claim 11 , wherein said isolating step provides an isolate containing said at least one antibody. 
     
     
         30 . The solid oral dosage form of  claim 29 , wherein said initial solution contains 0.05 to 3% of said isolate. 
     
     
         31 . (canceled)