Hepatoprotective traditional chinese medicine composition, preparation method and use thereof

Abstract

Disclosed is a hepatoprotective traditional Chinese medicine composition and a preparation method and use thereof. The composition is prepared by Fructus Ligustri Lucidi, Herba Ecliptae, Radix Paeoniae Alba, Rhizoma Curcumae Longae and clam. The present invention utilizes Fructus Ligustri Lucidi and Herba Ecliptae to nourish the liver blood, Radix Paeoniae Alba and Rhizoma Curcumae Longae to invigorate the liver qi circulation, and clam to detoxify the liver. It combines several medicines to nourish the liver, smooth the liver qi and achieves a liver nourishing and protective efficacy, and is applicable to the population suffering from liver injury caused by an unhealthy lifestyle. The composition is characterized in using Fructus Ligustri Lucidi, Herba Ecliptae, Radix Paeoniae Alba, Rhizoma Curcumae Longae and clam as main raw materials. It combines various components reasonably, uses them in conjunction, and achieves a health-care function via multiple means and at multiple levels.

1 . A hepatoprotective traditional Chinese medicine composition, which is prepared by  Fructus Ligustri Lucidi, Herba Ecliptae, Radix Paeoniae Alba, Rhizoma Curcumae Longae  and clam. 
     
     
         2 . The traditional Chinese medicine composition according to  claim 1 , which is prepared by extracting  Fructus Ligustri Lucidi, Herba Ecliptae  and  Radix Paeoniae Alba  with ethanol and then mixing with a  Rhizoma Curcumae Longae  extract and a clam extract, wherein the  Rhizoma Curcumae Longae  extract is an alcohol extract of  Rhizoma Curcumae Longae  and the clam extract is a water extract of clam. 
     
     
         3 . The traditional Chinese medicine composition according to  claim 2 , wherein the parts by weight of the respective components are:
 4-30 parts of  Fructus Ligustri Lucidi,  2-15 parts of  Herba Ecliptae,  2-15 parts of  Radix Paeoniae Alba,  2-20 parts of the  Rhizoma Curcumae Longae  extract, and 2-10 parts of the clam extract.   
     
     
         4 . The traditional Chinese medicine composition according to  claim 3 , wherein the parts by weight of the respective components are:
 10-25 parts of  Fructus Ligustri Lucidi,  5-15 parts of  Herba Ecliptae,  3-12 parts of  Radix Paeoniae Alba,  6-18 parts of the  Rhizoma Curcumae Longae  extract, and 4-8 parts of the clam extract.   
     
     
         5 . The traditional Chinese medicine composition according to  claim 4 , wherein the parts by weight of the respective components are:
 20 parts of  Fructus Ligustri Lucidi,  15 parts of  Herba Ecliptae,  8 parts of  Radix Paeoniae Alba,  12 parts of the  Rhizoma Curcumae Longae  extract, and 8 parts of the clam extract.   
     
     
         6 . The traditional Chinese medicine composition according to  claim 2 , wherein the  Rhizoma Curcumae Longae  extract is prepared by the following process:
 Grinding the  Rhizoma Curcumae Longae , then extracting it with ethanol, concentrating the extract solution under reduced pressure into an extractum, adding ethanol to dissolve the extractum, filtering, concentrating the filtrate, and drying to obtain the  Rhizoma Curcumae Longae  extract.   
     
     
         7 . The traditional Chinese medicine composition according to  claim 2 , wherein the clam extract is prepared by the following process:
 Washing the fresh clam, then boiling it with water, concentrating and filtering to obtain an extract solution of the clam, sterilizing, and then drying to obtain the clam extract.   
     
     
         8 . A method of preparing a hepatoprotective health product, comprising providing the traditional Chinese medicine composition according to  claim 1 . 
     
     
         9 . The method according to  claim 8 , wherein the hepatoprotective health product is in the form of oral liquid, capsule, tablet, powder or granule. 
     
     
         10 . A method for preparing the traditional Chinese medicine composition according to  claim 1 , comprising:
 step 1, extracting  Fructus Ligustri Lucidi, Herba Ecliptae  and  Radix Paeoniae Alba  with ethanol and concentrating the extract solution to obtain an alcohol extract of the three components;   step 2, mixing the alcohol extract of  Fructus Ligustri Lucidi, Herba Ecliptae  and  Radix Paeoniae Alba  with the  Rhizoma Curcumae Longae  extract and the clam extract to obtain the traditional Chinese medicine composition.