US2017073323A1PendingUtilityA1
Processes and intermediates for the preparations of isomer free prostaglandins
Est. expiryAug 15, 2033(~7.1 yrs left)· nominal 20-yr term from priority
A61P 27/06C07C 2601/08C07D 407/12C07C 231/02C07D 313/00C07D 407/14C07C 67/02C07C 69/618C07D 309/12C07C 69/52C07F 7/1804A61K 31/5575A61K 31/165C07C 405/0041C07C 405/00C07C 69/608C07C 405/0016C07C 59/72C07C 67/10C07C 51/347
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Abstract
Novel processes for the preparation of a compound of Formula I-2 substantially free of the 5,6-trans isomer: wherein R 2 , R 3 and R 4 are as defined in the specification are provided. Novel intermediates for the preparations of isomer free Prostaglandins and derivatives thereof are also provided.
Claims
exact text as granted — not AI-modified1 . A compound selected from the group consisting of:
wherein
and P 1 and P 2 are protecting groups for hydroxyl groups, which are independently selected from the group consisting of methoxymethyl, methoxythiomethyl, tert-butylthiomethyl, benzyloxymethyl, 2-methoxyethoxymethyl, bis(2-chloroethoxy)methyl, tetrahydropyranyl, tetrahydrothiopyranyl, 4-methoxytetrahydropyranyl, 4-methoxytetrahydrothiopyranyl, tetrahydrofuranyl, tetrahydrothiofuranyl, 1-ethoxyethyl, 1-methyl-1-methoxyethyl, and triphenylmethyl.Cited by (0)
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