Medication adherence monitoring device

Abstract

A Self Monitoring And Reporting Therapeutics, SMART® composition, method, apparatus and system are provided which flexibly provide options, by combining different embodiments of the device with different embodiments of the composition, the ability to conduct definitive medication adherence monitoring over the short term (Acute Medication Adherence Monitoring, immediately up to an hour or so after taking a medication), intermediate term (Intermediate Medication Adherence Monitoring, IMAM, an hour or so to a day or so after taking a medication), and longer term (Chronic Medication Adherence Monitoring, CMAM, a day to several days after taking a medication).

What is claimed is: 
     
         1 .- 35 . (canceled) 
     
     
         36 . An apparatus for identifying and/or quantitating volatile compounds in a gas sample comprising:
 at least one sensor adapted for identification and/or quantitation of a volatile compound of interest present in said gas sample; and   at least one capture device which releasably captures volatile compounds in said gas sample;   said apparatus further comprising a catalytic incinerator between said at least one capture device and said at least one sensor which converts said volatile compound of interest to carbon dioxide and water prior to contact with said at least one sensor.   
     
     
         37 . The apparatus of  claim 36 , wherein the capture device does not capture moisture, hydrogen, nitrogen, or carbon dioxide, in said gas sample, and which releases captured volatile compounds for sensing by said at least one sensor; 
     
     
         38 . The apparatus according to  claim 36  adapted for identifying and/or quantitating volatile compounds wherein said gas sample is comprised by exhaled breath of a subject, said apparatus further comprising at least one or a combination of:
 a. at least one biometric capture device for concurrent capture of a biometric specific to said subject when said gas sample is provided by said subject to said apparatus; 
 b. a mouthpiece for delivery of an exhaled breath sample by said subject to said apparatus, said mouthpiece being operatively coupled with an exhaled breath detection sensor; and 
 c. a push button on said apparatus that said subject can press to self-report adherence to a dose of a medication. 
 
     
     
         39 . The apparatus according to  claim 37  comprising at least two sensors with differential sensitivity to a volatile compound of interest in the exhaled breath of a subject. 
     
     
         40 . The apparatus according to  claim 36  comprising said catalytic incinerator wherein said at least one sensor is an infrared sensor adapted to detect water, carbon dioxide or both water and carbon dioxide containing non-ordinary but stable isotopes of carbon, oxygen or hydrogen.