System for left atrial appendage occlusion

Abstract

Disclosed is an occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device includes an occlusion member and may also include a stabilizing member. The stabilizing member inhibits compression of the left atrial appendage, facilitating tissue in-growth onto the occlusion member. Methods are also disclosed.

1 . (canceled) 
     
     
         2 . A device configured for implantation in a left atrial appendage, the device comprising:
 a support structure having a radially compressed configuration and a radially expanded configuration, wherein the support structure tapers radially inward from a proximal end of the support structure to a distal end of the support structure;   a membrane extending along at least part of a proximal portion of the support structure; and   one or more distal anchoring segments configured to engage a wall of the left atrial appendage extend radially outward from the distal end of the support structure,   wherein the one or more distal anchoring segments are provided with an atraumatic configuration.   
     
     
         3 . The device of  claim 2 , wherein the one or more distal anchoring segments extend radially outward in a proximal direction in the radially expanded configuration. 
     
     
         4 . The device of  claim 2 , comprising three anchoring segments provided with an atraumatic configuration. 
     
     
         5 . The device of  claim 2 , comprising 20 distal anchoring segments provided with an atraumatic configuration. 
     
     
         6 . The device of  claim 2 , wherein the support structure comprises a plurality of spokes joined to an axial hub. 
     
     
         7 . The device of  claim 6 , wherein each spoke of the plurality of spokes is forms cellular structures with one or more adjacent spokes to support the membrane. 
     
     
         8 . The device of  claim 2 , wherein a release element of a delivery device is provided with a releasable lock for attachment to the proximal end of the support structure. 
     
     
         9 . The device of  claim 8 , wherein the release element of a delivery device is adapted to be releaseably detached from the support structure within a left atrial appendage. 
     
     
         10 . The device of  claim 2 , wherein the membrane is a barrier membrane. 
     
     
         11 . The device of  claim 2 , wherein the membrane is a porous membrane. 
     
     
         12 . The device of  claim 2 , wherein the membrane includes openings or pores within a range of from about 0.0005 inches to about 0.010 inches. 
     
     
         13 . The device of  claim 2 , wherein the membrane is formed from materials which facilitate cellular in-growth. 
     
     
         14 . The device of  claim 2 , wherein the membrane is formed as a composite laminate. 
     
     
         15 . The device of  claim 2 , wherein the membrane covers substantially all of the support structure. 
     
     
         16 . The device of  claim 2 , wherein the support structure comprises a metal. 
     
     
         17 . The device of  claim 16 , wherein the support structure comprises a nitinol. 
     
     
         18 . The device of  claim 2 , wherein the support structure is self-expanding. 
     
     
         19 . The device of  claim 2 , wherein the support structure folds inward to form the radially compressed configuration. 
     
     
         20 . The device of  claim 2 , wherein in the radially expanded configuration the support structure is flexible to accommodate conforming to an irregular left atrial appendage opening. 
     
     
         21 . The device of  claim 2 , wherein the membrane covers a distally facing portion of the support structure.