US2017112938A1PendingUtilityA1

Pharmaceutical compositions and related methods of delivery

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Assignee: CHIASMA INCPriority: Sep 17, 2008Filed: Jan 3, 2017Published: Apr 27, 2017
Est. expirySep 17, 2028(~2.2 yrs left)· nominal 20-yr term from priority
A61P 7/04A61P 5/00A61P 5/08A61P 9/08A61P 37/00A61P 9/00A61P 9/14A61P 3/10A61P 5/06A61P 9/12A61P 5/02A61P 35/00A61P 3/00A61P 31/20A61P 25/00A61P 31/04A61P 31/14A61P 27/02A61P 3/04A61P 31/00A61P 1/16A61P 13/12A61P 1/04A61P 1/10A61P 1/14A61P 1/12A61P 1/00A61P 1/18A61K 9/4891A61K 47/24A61K 47/12A61K 38/27A61K 51/1024A61K 38/28A61K 38/08A61K 9/1623A61K 47/32A61K 9/4866A61K 38/29A61K 38/095A61K 47/44A61K 9/4858A61K 47/14A61K 31/70A61K 38/212A61K 9/10A61K 38/09A61K 38/26A61K 38/22A61K 38/12A61K 31/721A61K 38/14A61K 47/26A61K 51/1021A61K 9/0031A61K 31/713A61K 9/0053A61K 31/7036A61K 9/16A61K 47/34A61K 51/1045A61K 51/083A61K 9/08A61K 38/00A61K 38/31A61K 38/30A61K 38/2214A61K 38/16
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Claims

Abstract

The pharmaceutical compositions described herein include a suspension which comprises an admixture in solid form of a therapeutically effective amount of a therapeutic agent and at least one salt of a medium chain fatty acid and a hydrophobic medium, e.g. castor oil or glyceryl tricaprylate or a mixture thereof. The pharmaceutical compositions described herein contain medium chain fatty acid salts and are substantially free of alcohols. The pharmaceutical compositions may be encapsulated in a capsule. Methods of treating or preventing diseases by administering such compositions to affected subjects are also disclosed.

Claims

exact text as granted — not AI-modified
1 . A composition comprising a suspension which comprises an admixture of a hydrophobic medium and a solid form wherein the solid form comprises a therapeutically effective amount of a therapeutic agent and at least one salt of a medium chain fatty acid, and wherein the medium chain fatty acid salt is present in the composition at an amount of 10% or more by weight.

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