Devices for therapeutic vascular procedures

Abstract

Methods and devices for removing a thrombus are described. The device includes an expandable cylindrical structure made of wires and a self-expanding permeable shell located at the distal end of the cylindrical structure. Methods and devices for treating a cerebral aneurysm are described. The device may include a self-expanding resilient permeable shell and a metallic coil secured to the distal end of the permeable shell.

What is claimed: 
     
         1 . A device for treatment of an aneurysm within a patient's vasculature, comprising:
 a self-expanding resilient permeable shell having a proximal end, a distal end, and a longitudinal axis, the shell comprising a plurality of elongate resilient filaments having a braided structure, wherein the plurality of filaments are secured at least at one of the proximal end or the distal end thereof;   a metallic coil formed from a wire having a first diameter, wherein the metallic coil is secured at the distal end of the self-expanding resilient permeable shell;   wherein the permeable shell has a radially constrained elongated state configured for delivery within a microcatheter and has an expanded state with a globular, axially shortened configuration relative to the radially constrained state, the permeable shell having a plurality of openings formed between the braided filaments; and   wherein the metallic coil has a linear, straightened shape configured for delivery within a microcatheter.   
     
     
         2 . The device of  claim 1 , wherein the metallic coil is configured to place a bias on the permeable shell when the permeable shell is in the expanded state within an aneurysm. 
     
     
         3 . The device of  claim 1 , wherein the metallic coil when at least partially compressed in an axial direction applies an axial bias of at least 0.27 grams 
     
     
         4 . The device of  claim 1 , wherein the metallic coil when at least partially compressed in an axial direction applies an axial bias of at least 2.67 grams. 
     
     
         5 . The device of  claim 1 , wherein the metallic coil when at least partially compressed in an axial direction applies an axial bias, of at least 16.6 grams. 
     
     
         6 . The device of  claim 1 , wherein the metallic coil is configured to conform to a three-dimensional framing shape. 
     
     
         7 . The device of  claim 1 , wherein the metallic coil is formed from wire comprising platinum. 
     
     
         8 . The device of  claim 1 , wherein the metallic coil has an expanded state having at least one loop having a secondary diameter. 
     
     
         9 . A method for treating a cerebral aneurysm, comprising the steps of:
 providing an implant structure comprising;
 a sell expanding resilient permeable shell having a proximal end, a distal end, and a longitudinal axis, the shell comprising a plurality of elongate resilient filaments having a braided structure, wherein the plurality of filaments are secured at least at one of the proximal end or the distal end thereof; 
 a metallic coil formed from a wire having a first diameter, wherein the metallic coil is secured at the distal end of the self-expanding resilient permeable shell; 
 wherein the permeable shell has a radially constrained elongated state configured for delivery within a microcatheter and has an expanded state with a globular, axially shortened configuration relative to the radially constrained state, the permeable shell having a plurality of openings formed between the braided filaments; and 
 wherein the metallic coil has a linear, straightened shape configured for delivery within a microcatheter; 
   advancing the implant within a microcatheter to a region near the cerebral aneurysm;   deploying the implant within the cerebral aneurysm, the metallic coil positioned near a dome of the cerebral aneurysm and assuming the expanded state and the permeable shell assuming the expanded deployed state within the cerebral aneurysm; and   withdrawing the microcatheter from the region near the cerebral aneurysm after deploying the implant.   
     
     
         10 . The method of  claim 9 , wherein the metallic coil pushes the permeable shell against an opening of the cerebral aneurysm. 
     
     
         11 . The method of  claim 9 , wherein the metallic coil tracks around a diameter of the cerebral aneurysm. 
     
     
         12 . The method of  claim 9 , wherein the secondary diameter of the metallic coil is approximately equal to a diameter of the permeable shell. 
     
     
         13 . The method of  claim 9 , wherein the metallic coil, when at least partially compressed in an axial direction, applies an axial bias of at least 0.27 grams. 
     
     
         14 . The method of  claim 9 , wherein the metallic coil, when at least partially compressed in an axial direction applies an axial bias of at least 2.67 grams. 
     
     
         15 . The method of  claim 9 , wherein the metallic coil, when at least partially compressed in an axial direction, applies an axial bias of at least 16.6 grams. 
     
     
         16 . The method of  claim 9 , wherein the metallic coil has an expanded state having at least one loop having a secondary diameter.