US2017135983A1PendingUtilityA1

Composition for regulating blood sugar

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Assignee: SUNWAY BIOTECH CO LTDPriority: Nov 13, 2015Filed: Aug 25, 2016Published: May 18, 2017
Est. expiryNov 13, 2035(~9.3 yrs left)· nominal 20-yr term from priority
Inventors:Tzu-Ming PanChun-Lin LeeYa-Wen Hsu
A61P 3/10A61P 39/06A61P 5/50A61P 3/08A61P 3/06A61P 3/00A61K 36/062A61K 31/366A61K 36/8945A61K 36/06A61P 1/16A61K 36/88A61K 31/352A61K 2300/00A61K 2236/19
39
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Claims

Abstract

The present invention provides a composition for regulating blood sugar. The composition comprises at least one yellow pigment extracted from a red mold product, wherein the said yellow pigment is Monascin, Ankaflavin, or combination of Monascin and Ankaflavin. Moreover, results of a variety of animal experiments have proved that this blood sugar regulating composition indeed possess the functionalities of: lowering Hyperglycemia induced by high energy diet, alleviating ROS and inflammatory caused by the Hyperglycemia, reduce AST and ALT value of liver as well as sarcosine value of kidney.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A composition for regulating blood sugar, comprising a yellow pigment extracted from a red mold product, wherein the said yellow pigment is Monascin, and a daily dosage of the Monascin for an adult user to regulate blood sugar is above 3 mg. 
     
     
         2 . The composition for regulating blood sugar of  claim 1 , wherein the red mold product is produced by inoculating a  Monascus purpureus  to a substrate and then subjecting the inoculated substrate with a culturing and drying process. 
     
     
         3 . The composition for regulating blood sugar of  claim 1 , wherein the Monascin with the daily dosage can also lower insulin resistance induced by Hyperglycemia. 
     
     
         4 . The composition for regulating blood sugar of  claim 1 , wherein the Monascin with the daily dosage can also lower the increasing of Triglycerides (TG) induced by Hyperglycemia. 
     
     
         5 . The composition for regulating blood sugar of  claim 1 , wherein the Monascin with the daily dosage can also lower the increasing of ROS (Reactive oxygen species) induced by Hyperglycemia. 
     
     
         6 . The composition for regulating blood sugar of  claim 1 , wherein the Monascin with the daily dosage can also alleviate the decreasing of glucose transporter (GLUT) caused by Hyperglycemia. 
     
     
         7 . The composition for regulating blood sugar of  claim 1 , wherein the Monascin with the daily dosage can also lower the increasing of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in liver induced by Hyperglycemia. 
     
     
         8 . The composition for regulating blood sugar of  claim 1 , wherein the Monascin with the daily dosage can also lower the increasing of sarcosine in kidney induced by Hyperglycemia. 
     
     
         9 . The composition for regulating blood sugar of  claim 2 , wherein the substrate is a rice substrate or a  Dioscorea  substrate. 
     
     
         10 . A composition for regulating blood sugar, comprising a yellow pigment extracted from a red mold product, wherein the said yellow pigment is Ankaflavin, and a daily dosage of the Ankaflavin for an adult user to regulate blood sugar is above 1.5 mg. 
     
     
         11 . The composition for regulating blood sugar of  claim 10 , wherein the red mold product is produced by inoculating a  Monascus purpureus  to a substrate and then subjecting the inoculated substrate with a culturing and drying process. 
     
     
         12 . The composition for regulating blood sugar of  claim 10 , wherein the Ankaflavin with the daily dosage can also lower insulin resistance induced by Hyperglycemia. 
     
     
         13 . The composition for regulating blood sugar of  claim 10 , wherein the Ankaflavin with the daily dosage can also lower the increasing of Triglycerides (TG) induced by Hyperglycemia. 
     
     
         14 . The composition for regulating blood sugar of  claim 10 , wherein the Ankaflavin with the daily dosage can also lower the increasing of ROS (Reactive oxygen species) induced by Hyperglycemia. 
     
     
         15 . The composition for regulating blood sugar of  claim 10 , wherein the Ankaflavin with the daily dosage can also alleviate the decreasing of glucose transporter (GLUT) caused by Hyperglycemia. 
     
     
         16 . The composition for regulating blood sugar of  claim 10 , wherein the Ankaflavin with the daily dosage can also lower the increasing of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in liver induced by Hyperglycemia. 
     
     
         17 . The composition for regulating blood sugar of  claim 10 , wherein the Ankaflavin with the daily dosage can also lower the increasing of sarcosine in kidney induced by Hyperglycemia. 
     
     
         18 . The composition for regulating blood sugar of  claim 11 , wherein the substrate is a rice substrate or a  Dioscorea  substrate. 
     
     
         19 . A composition for regulating blood sugar, comprising two yellow pigments extracted from a red mold product, wherein the said two yellow pigment are Monascin with first daily dosage of above 3 mg and Ankaflavin with second daily dosage of above 1.5 mg, therefore a total daily dosage of the composition for an adult user to regulate blood sugar is above 4.5 mg. 
     
     
         20 . The composition for regulating blood sugar of  claim 19 , wherein the red mold product is produced by inoculating a  Monascus purpureus  to a substrate and then subjecting the inoculated substrate with a culturing and drying process. 
     
     
         21 . The composition for regulating blood sugar of  claim 19 , wherein the composition with the total daily dosage can also lower insulin resistance induced by Hyperglycemia. 
     
     
         22 . The composition for regulating blood sugar of  claim 19 , wherein the composition with the total daily dosage can also lower the increasing of Triglycerides (TG) induced by Hyperglycemia. 
     
     
         23 . The composition for regulating blood sugar of  claim 19 , wherein the composition with the total daily dosage can also lower the increasing of ROS (Reactive oxygen species) induced by Hyperglycemia. 
     
     
         24 . The composition for regulating blood sugar of  claim 19 , wherein the composition with the total daily dosage can also alleviate the decreasing of glucose transporter (GLUT) caused by Hyperglycemia. 
     
     
         25 . The composition for regulating blood sugar of  claim 19 , wherein the composition with the total daily dosage can also lower the increasing of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in liver induced by Hyperglycemia. 
     
     
         26 . The composition for regulating blood sugar of  claim 19 , wherein the composition with the total daily dosage can also lower the increasing of sarcosine in kidney induced by Hyperglycemia. 
     
     
         27 . The composition for regulating blood sugar of  claim 20 , wherein the substrate is a rice substrate or a  Dioscorea  substrate. 
     
     
         28 . A composition for regulating blood sugar, being a red mold product produced by inoculating a  Monascus purpureus  to a substrate and then subjecting the inoculated substrate with a culturing and drying process; wherein a daily dosage of the red mold product for an adult user to regulate blood sugar is above 1 g. 
     
     
         29 . The composition for regulating blood sugar of  claim 28 , wherein the substrate is a rice substrate or a  Dioscorea  substrate. 
     
     
         30 . The composition for regulating blood sugar of  claim 28 , wherein the red mold product with the daily dosage can also lower insulin resistance induced by Hyperglycemia. 
     
     
         31 . The composition for regulating blood sugar of  claim 28 , wherein the composition with the total daily dosage can also lower the increasing of Triglycerides (TG) induced by Hyperglycemia. 
     
     
         32 . The composition for regulating blood sugar of  claim 28 , wherein the composition with the total daily dosage can also lower the increasing of ROS (Reactive oxygen species) induced by Hyperglycemia. 
     
     
         33 . The composition for regulating blood sugar of  claim 28 , wherein the composition with the total daily dosage can also alleviate the decreasing of glucose transporter (GLUT) caused by Hyperglycemia. 
     
     
         34 . The composition for regulating blood sugar of  claim 28 , wherein the composition with the total daily dosage can also lower the increasing of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in liver induced by Hyperglycemia. 
     
     
         35 . The composition for regulating blood sugar of  claim 28 , wherein the composition with the total daily dosage can also lower the increasing of sarcosine in kidney induced by Hyperglycemia.

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