Medication With A Reduced Bitter Taste Perception

Abstract

A liquid medication with reduced bitterness containing a drug active and polyquaternium-2, polyquaternium-17, and/or polyquaternium-18.

What is claimed is: 
     
         1 . A medication with reduced bitterness comprising:
 a. a drug active, wherein the drug active is selected from the group consisting of guaifenesin, phenytoin, omeprazole, cetirizine, jambu, acetaminophen, and combinations thereof; and   b. a polyquaternium selected from the group consisting of polyquaternium-2, polyquaternium-17, polyquaternium-18, and combinations thereof.   
     
     
         2 . The medication of  claim 1  wherein the drug active comprises guaifenesin. 
     
     
         3 . The mediation of  claim 2  wherein the drug active further comprises acetaminophen. 
     
     
         4 . The medication of  claim 1  wherein the medication comprises from about 0.0001% to about 1% of the polyquaternium. 
     
     
         5 . The medication of  claim 1  wherein the medication comprises from about 0.001% to about 1% of the polyquaternium. 
     
     
         6 . The medication of  claim 1  wherein the medication comprises from about 0.03% to about 0.3% of the polyquaternium. 
     
     
         7 . The medication of  claim 1  wherein the medication comprises less than about 0.2% of the polyquaternium-2. 
     
     
         8 . The medication of  claim 1  wherein the medication is selected from a liquid, a tablet, a powder and combinations thereof. 
     
     
         9 . The medication of  claim 1  further comprising a sensate. 
     
     
         10 . The medication of  claim 1  wherein an overall bitterness is less than about 7000 fluorescence units as determined by the in vitro Assay for Taste Receptors. 
     
     
         11 . A dose of medication with reduced bitterness comprising:
 a. at least about 200 mg guaifenesin;   b. from about 0.05% to about 0.2% of a polyquaternium selected from the group consisting of polyquaternium-2, polyquaternium-17, polyquaternium-18, and combinations thereof.   
     
     
         12 . The dose of medication of  claim 11  wherein the polyquaternium is polyquaternium-2. 
     
     
         13 . The dose of medication of  claim 11  further comprising an antihistamine, an antitussive, a pain reliever and combinations thereof. 
     
     
         14 . The dose of medication of claim  113  further comprising from about 325 mg to about 500 mg of the pain reliever. 
     
     
         15 . The dose of medication of  claim 11  wherein the pain reliever is acetaminophen. 
     
     
         16 . The dose of medication of  claim 15  further comprising dextromethorphan hydrobromide and phenylephrine. 
     
     
         17 . The dose of medication of  claim 16  comprising about 5 mg phenylephrine. 
     
     
         18 . The dose of medication of  claim 16  comprising about 10 mg dextromethorphan hydrobromide.