Attribute Combination Discovery for Predisposition Determination

Abstract

A method and system are presented in which a query attribute is used as the basis for accessing stored attribute combinations and their frequencies of occurrence for query-attribute-positive individuals and query-attribute-negative individuals and tabulating, based on frequencies of occurrence, those attribute combinations that are most likely to co-occur with the query attribute.

1 . A computer-based method for generating a recommendation indicating a treatment for a medical condition which the individual is subject to, the computer including a user interface, a processor, a memory, and a display, the computer-based method comprising:
 a) receiving at the processor, via the user interface, a query to report on the at least one medical condition with respect to the individual;   b) accessing via the processor an attribute profile associated with the individual, wherein the attribute profile contains pangenetic and non-pangenetic attributes, the pangenetic attributes comprising genetic or epigenetic attributes;   c) accessing via the processor a dataset, stored in the memory, which contains pangenetic attributes, non-pangenetic attributes, treatment regimes, and treatment regime outcomes for a reference set of individuals, the pangenetic attributes comprising genetic or epigenetic attributes;   d) calculating with the processor attribute combinations and a strength of association of the attribute combinations with a successful treatment regime of the reference set of individuals, wherein the attribute combinations contain at least one non-pangenetic attribute;   e) identifying from the attribute combinations of d) and the attributes of the individual a proposed treatment regime for the individual; and   f) generating output for display indicating the proposed treatment regime for the at least one medical condition based on the identified attribute combinations.   
     
     
         2 . The computer based method of  claim 1 , wherein the at least one non-pangenetic attribute is smoking related. 
     
     
         3 . The computer based method of  claim 1 , wherein the at least one non-pangenetic attribute is alcohol consumption related. 
     
     
         4 . The computer based method of  claim 1 , wherein the at least one non-pangenetic attribute is exercise related. 
     
     
         5 . The computer-based method of  claim 1 , wherein the medical condition is skin related and the recommendation is a skin treatment regime. 
     
     
         6 . The computer-based method of  claim 1 , wherein the medical condition is weight related and the recommendation is a weight loss regime. 
     
     
         7 . The computer-based method of  claim 1 , wherein the medical condition is mental health related and the recommendation is a mental health treatment regime. 
     
     
         8 . The computer-based method of  claim 2 , wherein the medical condition is skin related and the recommendation is a skin treatment regime. 
     
     
         9 . The computer-based method of  claim 2 , wherein the medical condition is weight related and the recommendation is a weight loss regime. 
     
     
         10 . The computer-based method of  claim 2 , wherein the medical condition is mental health related and the recommendation is a mental health treatment regime. 
     
     
         11 . The computer-based method of  claim 3 , wherein the medical condition is skin related and the recommendation is a skin treatment regime. 
     
     
         12 . The computer-based method of  claim 3 , wherein the medical condition is weight related and the recommendation is a weight loss regime. 
     
     
         13 . The computer-based method of  claim 3 , wherein the medical condition is mental health related and the recommendation is a mental health treatment regime. 
     
     
         14 . The computer-based method of  claim 4 , wherein the medical condition is skin related and the recommendation is a skin treatment regime. 
     
     
         15 . The computer-based method of  claim 4 , wherein the medical condition is weight related and the recommendation is a weight loss regime. 
     
     
         16 . The computer-based method of  claim 4 , wherein the medical condition is mental health related and the recommendation is a mental health treatment regime. 
     
     
         17 . A computer readable storage medium containing instructions which when executed by a computer result in the execution of a method for generating a recommendation indicating a treatment for a medical condition which the individual is subject to, the method comprising:
 a) receiving at the processor, via the user interface, a query to report on the at least one medical condition with respect to the individual;   b) accessing via the processor an attribute profile associated with the individual, wherein the attribute profile contains pangenetic and non-pangenetic attributes, the pangenetic attributes comprising genetic or epigenetic attributes;   c) accessing via the processor a dataset, stored in the memory, which contains pangenetic attributes, non-pangenetic attributes, treatment regimes, and treatment regime outcomes for a reference set of individuals, the pangenetic attributes comprising genetic or epigenetic attributes;   d) calculating with the processor attribute combinations and a strength of association of the attribute combinations with a successful treatment regime of the reference set of individuals, wherein the attribute combinations contain at least one non-pangenetic attribute;   e) identifying from the attribute combinations of d) and the attributes of the individual a proposed treatment regime for the individual; and   f) generating output for display indicating the proposed treatment regime for the at least one medical condition based on the identified attribute combinations.   
     
     
         18 . The computer based method of  claim 17 , wherein the at least one non-pangenetic attribute is smoking related. 
     
     
         19 . The computer based method of  claim 17 , wherein the at least one non-pangenetic attribute is alcohol consumption related. 
     
     
         20 . The computer based method of  claim 17 , wherein the at least one non-pangenetic attribute is exercise related.