US2017204041A1PendingUtilityA1
Processes for preparing (r)-1-(5-chloro-[1,1`-biphenyl]-2-yl)-2,2,2-trifluoroethanol and 1-(5-chloro-[1,1`-biphenyl]-2-yl)-2,2,2-trifluoroethanone
Est. expiryMar 5, 2035(~8.6 yrs left)· nominal 20-yr term from priority
C07C 29/32C07C 259/10C07C 45/455C07C 49/80C07C 29/143C07B 2200/07
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Abstract
The present invention relates to processes for the preparation of (R)-1-(5-chloro-[1,1′-biphenyl]-2-yl)-2,2,2-trifluoroethanol, 1-(5-chloro-[1,1′-biphenyl]-2-yl)-2,2,2-trifluoroethanone, and intermediates thereof, which are useful in the preparation of inhibitors of TPH1 for the treatment of, for example, gastrointestinal, cardiovascular, pulmonary, inflammatory, metabolic, low bone mass diseases, serotonin syndrome, and cancer.
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exact text as granted — not AI-modified1 - 81 . (canceled)
82 . A compound which is a compound of Formula B:
83 . A compound which is a compound of Formula 1-3:
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