Immunoreactive protein orthologs of ehrlichia canis and e. chaffeensis

Abstract

The present invention concerns gp36 immunoreactive compositions for E. canis and gp 47 immunoreactive compositions for E. chaffeensis . In particular, epitopes for E. canis gp36 and E. chaffeensis gp 47 are disclosed. In certain embodiments, the immunoreactive compositions comprise tandem repeats having carbohydrate moieties.

1 .- 35 . (canceled) 
     
     
         36 . An isolated antibody that recognizes and binds immunologically to a polypeptide selected from the group consisting of SEQ ID NO:22, SEQ ID NO:45, SEQ ID NO:46, SEQ ID NO:23, and SEQ ID NO:24 or a polypeptide that is at least 95% identical to such a polypeptide, wherein the antibody is either bound to a solid support or a detectable label. 
     
     
         37 . The antibody of  claim 36 , wherein the antibody is a monoclonal antibody, is comprised in polyclonal antisera, or is an antibody fragment. 
     
     
         38 . The antibody of  claim 37 , wherein the antibody is a monoclonal antibody. 
     
     
         39 . The antibody of  claim 37 , wherein the antibody is comprised in polyclonal antisera. 
     
     
         40 . The antibody of  claim 36 , wherein the polypeptide consists of SEQ ID NO:22. 
     
     
         41 . The antibody of  claim 36 , wherein the polypeptide consists of SEQ ID NO:45. 
     
     
         42 . The antibody of  claim 36 , wherein the polypeptide consists of SEQ ID NO:46. 
     
     
         43 . The antibody of  claim 36 , wherein the polypeptide consists of SEQ ID NO:23. 
     
     
         44 . The antibody of  claim 36 , wherein the polypeptide consists of SEQ ID NO:24. 
     
     
         45 . The antibody of  claim 36 , wherein the detectable label is a radioactive label, a fluorescent label, a chemiluminescent label, an enzyme label, or a paramagnetic label.