External wound-healing agent, and external wound-healing material

Abstract

An external wound-healing agent includes, as an active ingredient, at least one compound of a glycerol alkyl ester represented by Formula (I) or a diglycerol alkyl ester represented by Formula (II).

1 . An external wound-healing agent comprising, as an active ingredient,
 at least one compound of a glycerol alkyl ester or a diglycerol alkyl ester,   the glycerol alkyl ester represented by the following Formula (I):   
       
         
           
           
               
               
           
         
         wherein, in Formula (I), each of R 1 , R 2 , and R 3  independently represents a hydrogen atom or an acyl group having from 12 to 22 carbon atoms, and at least one of R 1 , R 2 , or R 3  is an acyl group having from 12 to 22 carbon atoms, 
         the diglycerol alkyl ester represented by the following Formula (II): 
       
       
         
           
           
               
               
           
         
         wherein, in Formula (II), each of R 4 , R 5 , R 6 , and R 7  independently represents a hydrogen atom or an acyl group having from 12 to 22 carbon atoms, and at least one of R 4 , R 5 , R 6 , or R 7  is an acyl group having from 12 to 22 carbon atoms. 
       
     
     
         2 . The external wound-healing agent according to  claim 1 , wherein the glycerol alkyl ester is at least one of glycerol palmitate or glycerol stearate, and the diglycerol alkyl ester is at least one of diglycerol palmitate or diglycerol stearate. 
     
     
         3 . An external wound-healing material comprising:
 a fiber aggregate; or   a film,   
       the fiber aggregate or the film each comprising:
 a thermoplastic resin; and 
 at least one compound of a glycerol alkyl ester or a diglycerol alkyl ester, 
 the glycerol alkyl ester represented by the following Formula (I): 
 
       
         
           
           
               
               
           
         
         wherein, in Formula (I), each of R 1 , R 2 , and R 3  independently represents a hydrogen atom or an acyl group having from 12 to 22 carbon atoms, and at least one of R 1 , R 2 , or R 3  is an acyl group having from 12 to 22 carbon atoms, 
         the diglycerol alkyl ester represented by the following Formula (II): 
       
       
         
           
           
               
               
           
         
         wherein, in Formula (II), each of R 4 , R 5 , R 6 , and R 7  independently represents a hydrogen atom or an acyl group having from 12 to 22 carbon atoms, and at least one of R 4 , R 5 , R 6 , or R 7  is an acyl group having from 12 to 22 carbon atoms. 
       
     
     
         4 . The external wound-healing material according to  claim 3 , wherein the glycerol alkyl ester is at least one of glycerol palmitate or glycerol stearate, and the diglycerol alkyl ester is at least one of diglycerol palmitate or diglycerol stearate. 
     
     
         5 . The external wound-healing material according to  claim 3 , wherein the thermoplastic resin is at least one resin selected from the group consisting of olefin resins, urethane resins, amide resins, ester resins, acrylic resins, styrene resins, and carbonate resins. 
     
     
         6 . The external wound-healing material according to  claim 5 , wherein the thermoplastic resin is an olefin resin. 
     
     
         7 . The external wound-healing material according to  claim 5 , wherein the olefin resin is at least one of an ethylene copolymer or a propylene copolymer. 
     
     
         8 . The external wound-healing material according to  claim 3 , wherein the fiber aggregate is a nonwoven fabric.