Methods for treating ocular contusion and blunt injury and traumatic injury of the optic nerve

Abstract

The invention is directed to methods for treating ocular contusion and blunt injury to the eye and for treating traumatic injury of the optic nerve. The invention is further directed to treating ocular contusion and blunt injury to the eye and for treating traumatic injury of the optic nerve by administering to a subject suffering from such conditions Amnion-derived Cellular Cytokine Solution (ACCS), including novel immediate-release, targeted-release, and sustained-release (SR) ACCS compositions (referred to herein as “SR-ACCS” compositions) and/or and Amnion-derived Multipotent Progenitor (AMP) cell compositions. Such administration includes intranasal administration of ACCS and/or AMP cells.

1 .- 12 . (canceled) 
     
     
         13 . A method for treating visual dysfunction following traumatic injury to ocular structures in a patient in need thereof comprising administering to the patient a therapeutically effective amount of a composition selected from the group consisting of Amnion-derived Cellular Cytokine Solution (ACCS) and Amnion-derived Multipotent Progenitor (AMP) cells. 
     
     
         14 . The method of  claim 14  wherein the ACCS or the AMP cells are formulated for intranasal administration, topical administration or administration by intraocular injection. 
     
     
         15 . The method of  claim 14  wherein the intranasal administration is aerosol or spray administration. 
     
     
         16 . The method of  claim 13  wherein the ACCS is formulated as a lyophilized dry powder nasal formulation. 
     
     
         17 . The method of  claim 13  wherein the administration is intranasal administration. 
     
     
         18 . The method of  claim 13  wherein the administration is intraocular administration. 
     
     
         19 . The method of  claim 13  wherein the administration is topical administration.