Methods for treating acute acoustic trauma

Abstract

The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The composition 2,4-disulfonyl α-phenyl tertiary butyl nitrone and N-acetylcysteine (NAC). Preferably, the compositions for treating AAT will be administered orally. However, other methods which deliver the compositions for treating AAT systemically to the body should work equally well.

1 - 20 . (canceled) 
     
     
         21 . A method for treating a patient diagnosed with Meniere's disease comprising administering orally to a patient in need thereof a therapeutically effective amount of 2,4-disulfonyl α-phenyl tertiary butyl nitrone or pharmaceutically acceptable salts thereof. 
     
     
         22 . A method for treating a patient diagnosed with Meniere's disease comprising administering orally to a patient in need thereof a therapeutically effective amount of 2,4-disulfonyl α-phenyl tertiary butyl nitrone or pharmaceutically acceptable salts thereof in combination with a therapeutically effective amount of N-acetylcysteine or pharmaceutically acceptable salts thereof. 
     
     
         23 . The method of  claim 22 , in which the active ingredients are administered in separate dosage forms. 
     
     
         24 . The method of  claim 22 , in which the active ingredients are administered in the same dosage form.