US2017233333A1PendingUtilityA1

Process for the synthesis of (+) and (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane

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Assignee: EUTHYMICS BIOSCIENCE INCPriority: Apr 28, 2006Filed: Dec 2, 2016Published: Aug 17, 2017
Est. expiryApr 28, 2026(expired)· nominal 20-yr term from priority
A61P 25/24A61P 25/22A61P 25/00C07C 215/20C07C 255/46C07C 2601/02C07C 211/29C07C 215/38C07D 209/52A61P 13/02A61K 31/403
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Claims

Abstract

The present invention is concerned with novel processes for the preparation of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., depression, anxiety disorders, eating disorders and urinary incontinence.

Claims

exact text as granted — not AI-modified
1 - 13 . (canceled) 
     
     
         14 . A compound selected from the group consisting of: 
       
         
           
           
               
               
           
         
       
       or a salt thereof. 
     
     
         15 . The compound of  claim 14 , wherein the compound is 
       
         
           
           
               
               
           
         
       
       or a salt thereof. 
     
     
         16 . The compound of  claim 14 , wherein the compound is 
       
         
           
           
               
               
           
         
       
       or a salt thereof. 
     
     
         17 . A compound selected from the group consisting of: 
       
         
           
           
               
               
           
         
       
       or a salt thereof. 
     
     
         18 . The compound of  claim 17 , wherein the compound is 
       
         
           
           
               
               
           
         
       
       or a salt thereof. 
     
     
         19 . The compound of  claim 17 , wherein the compound is 
       
         
           
           
               
               
           
         
       
       or a salt thereof. 
     
     
         20 . A compound selected from the group consisting of: 
       
         
           
           
               
               
           
         
       
       or a salt thereof. 
     
     
         21 . The compound of  claim 20 , wherein the compound is 
       
         
           
           
               
               
           
         
       
       or a salt thereof. 
     
     
         22 . The compound of  claim 20 , wherein the compound is 
       
         
           
           
               
               
           
         
       
       or a salt thereof.

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