US2017246108A1PendingUtilityA1

Production of unit dose constructs

67
Assignee: ARX LLCPriority: Jan 23, 2013Filed: May 17, 2017Published: Aug 31, 2017
Est. expiryJan 23, 2033(~6.5 yrs left)· nominal 20-yr term from priority
A61K 9/7007A61K 9/006A61K 47/38A61K 47/34
67
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Claims

Abstract

Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose construct is formed by providing a first composition including a water soluble polymer and a liquid carrier, depositing the first composition onto a substrate, providing a second composition including a water soluble polymer and a liquid carrier, applying the second composition at a discrete location overlying the first composition by microdeposition; and removing at least a portion of the liquid carrier from the first composition to form the unit dose construct.

Claims

exact text as granted — not AI-modified
1 . A method of forming a dissolvable unit dose construct comprising:
 providing a first composition comprising a water soluble polymer and a liquid carrier;   depositing the first composition onto a substrate;   providing a second composition comprising a water soluble polymer and a liquid carrier;   applying the second composition at a discrete location overlying the first composition by microdeposition; and   removing at least a portion of the liquid carrier from the first composition to form a unit dose construct.   
     
     
         2 . The method of  claim 1 , further comprising removing the portion of the liquid carrier from the first composition prior to the step of applying the second composition. 
     
     
         3 . The method of  claim 1 , comprising forming a first unit dose construct and thereafter forming a second unit dose construct, wherein the first unit dose construct contains a volume of the second composition greater than the second unit dose construct. 
     
     
         4 . The method of  claim 3 , wherein the first and second individual units contain a same volume of the first composition. 
     
     
         5 . The method of  claim 3 , wherein the first and second compositions are formed as films. 
     
     
         6 . The method of  claim 1 , comprising depositing the first composition on the substrate as individual units. 
     
     
         7 . The method of  claim 1 , wherein the second composition further comprises an active ingredient. 
     
     
         8 . The method of  claim 1 , wherein the first composition further comprises an active ingredient. 
     
     
         9 . The method of  claim 1 , further comprising
 providing a third composition comprising a water soluble polymer and a liquid carrier;   depositing the third composition overlying a portion of the first composition,   wherein a first unit dose construct comprises the first and second compositions and a second unit dose construct comprises the first and third compositions.   
     
     
         10 . The method of  claim 9 , wherein the first individual unit dose construct consists of the first and second compositions and the second individual unit dose construct consists of the first and third compositions. 
     
     
         11 . The method of  claim 1 , further comprising
 providing a third composition comprising a water soluble polymer and a liquid carrier; and   depositing the third composition overlying a portion of the first composition at a location discrete from the location of the applied second composition, such that a single unit dose construct comprises each of the first, second and third compositions.

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