US2017290336A1PendingUtilityA1

Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom

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Assignee: MARRONE BIO INNOVATIONS INCPriority: Feb 25, 2010Filed: Jun 2, 2017Published: Oct 12, 2017
Est. expiryFeb 25, 2030(~3.6 yrs left)· nominal 20-yr term from priority
Inventors:Ratnakar AsolkarMarja KoivunenPamela MarroneAna Lucia Cordova-KreylosHuazhang Huang
C07D 309/14A01N 43/86C12P 17/16C07D 407/06C12P 17/14C07D 263/34C12N 1/20C12P 17/04C07D 413/04C07D 263/32C07D 513/04C12P 17/06A01N 43/90C07D 493/10A01N 43/16C07D 498/14A01N 43/00C07D 413/06C12P 17/18A01N 57/20C12R 1/01A01N 63/02A01N 43/76A01N 63/00C12R 2001/01C12R 2001/00C12N 1/205C12N 1/00A01N 63/20
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Claims

Abstract

A species of Burkholderia sp with no known pathogenicity to vertebrates but with pesticidal activity (e.g., plants, insects, fungi, weeds and nematodes) is provided. Also provided are natural products derived from a culture of said species and methods of controlling pests using said natural products.

Claims

exact text as granted — not AI-modified
1 .- 21 . (canceled) 
     
     
         22 . A method for inhibiting a pest infestation in a location where inhibition is desired comprising the steps of:
 applying an effective amount of a FR901888 compound isolated from a fermented whole cell broth collected from  Burkholderia  sp.,and   inhibiting the pest infestation at said location.   
     
     
         23 . The method according to  claim 22 , wherein said  Burkholderia  sp. is  Burkholderia  A396 strain. 
     
     
         24 . The method according to  claim 22 , wherein said pest infestation comprises  Diabrotica  or  Diptera.    
     
     
         25 . The method according to  claim 22 , wherein said pest infestation comprises  Aedes  spp. or  Culex  spp. 
     
     
         26 . The method according to  claim 24  wherein said  Aedes  spp. comprises  Aedes aegypti  or  Aedes albopictus.    
     
     
         27 . The method according to  claim 22 , wherein said  Diptera  is inhibited by increasing the mortality of said  Diptera.    
     
     
         28 . The method according to  claim 22 , wherein the infestation of  Diptera  is inhibited by decreasing the rate of hatching of eggs. 
     
     
         29 . The method according to  claim 22 , wherein the mortality of  Diptera  is increased and wherein there is a mortality of  Diptera  of at least about 50% at said location. 
     
     
         30 . The method according to  claim 22 , which further comprises applying a second 
     
     
         31 . A method for inhibiting a pest infestation in a location where inhibition is desired comprising the steps of:
 applying an effective amount of a FR901888 compound to inhibit the pest infestation.   
     
     
         32 . The method according to  claim 31 , wherein said pest infestation comprises  Diabrotica  or  Diptera.

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