Pump System for Inline Conditioning

Abstract

A pump system is disclosed. The pump system includes a cavity ( 102 ) comprising one or more inlet check valves ( 120, 122 ) and one or more outlet check valves ( 124, 126 ). A piston ( 104 ) having an enlargement ( 106 ) at a substantially middle portion of the piston ( 104 ). The piston ( 104 ) is capable of moving within the cavity ( 102 ) for forming a first chamber ( 116 ) and a second chamber ( 118 ), wherein up movement of the piston ( 104 ) the volume in the first chamber ( 112 ) is increased and simultaneously the volume in the second chamber ( 118 ) is decreased and vice versa.

We claim: 
     
         1 . An inline conditioning system comprising:
 a pump system comprising:
 a cavity comprising at least one inlet check valve and at least one outlet check valve; and 
 a piston having an enlargement at a substantially middle portion of the piston, wherein the piston is capable of moving within the cavity for forming a first chamber and a second chamber and receiving a solution within the cavity, wherein upon movement of the piston the volume in the first chamber is increased and simultaneously the volume in the second chamber is decreased and vice versa. 
   
     
     
         2 . The inline conditioning system of  claim 1 , wherein the piston have a first extension and a second extension at opposite ends of the enlargement, the first extension and the second extension having smaller configuration compared to the enlargement. 
     
     
         3 . The inline conditioning system of  claim 2  further comprising:
 a driving unit connected to the first extension for moving the piston; and 
 a resilient unit connected to the second extension for retrieving the position of the piston. 
 
     
     
         4 . The inline conditioning system of  claim 1 , wherein the piston having an extension at an end of the enlargement, the extension having smaller configuration compared to the enlargement, the inline conditioning system comprising a driving unit connected to the extension for moving the piston. 
     
     
         5 . The inline conditioning system of  claim 1 , wherein movement of the piston facilitates receiving a solution within the cavity through an inlet check valve and supplying the solution outside the cavity through an outlet check valve. 
     
     
         6 . The inline conditioning system of  claim 1 , wherein when the solution is used for inline conditioning in a chromatography system, the solution is one of acid, base, salt and buffer. 
     
     
         7 . The inline conditioning system of  claim 1 , wherein an inlet check valve of the at least one inlet check valve is configured at opposite orientation as compared to the orientation of an outlet check valve of the at least one outlet check valve. 
     
     
         8 . The inline conditioning system of  claim 1 , wherein upon moving the piston from the first chamber to the second chamber the solution is received within the first chamber through an inlet check valve configured at the first chamber and the solution is supplied out from the second chamber through an outlet check valve configured at the second chamber. 
     
     
         9 . The inline conditioning system of  claim 8 , wherein upon moving the piston from the second chamber to the first chamber the solution is received within the second chamber through an inlet check valve configured at the second chamber and the solution is supplied out from the first chamber through an outlet check valve configured at the first chamber. 
     
     
         10 . The inline conditioning system of  claim 1 , wherein the piston having an extension at the enlargement, the inline conditioning system comprising a driving unit connected to an end of the extension for moving the piston, wherein the driving unit is configured to vary the motor speed for varying the speed of movement of the piston. 
     
     
         11 . The inline conditioning system of  claim 1 , wherein a buffer preparation unit or a mixer is connected to the pump system for receiving the solution for buffer preparation.