US2017348248A1PendingUtilityA1

Gel Patch

48
Assignee: HISAMITSU PHARMACEUTICAL COPriority: Dec 22, 2014Filed: Dec 14, 2015Published: Dec 7, 2017
Est. expiryDec 22, 2034(~8.4 yrs left)· nominal 20-yr term from priority
Inventors:Keiichiro TsurushimaYasuhisa KoseTakaaki Yoshinaga
A61K 9/7061A61K 47/14A61K 31/618A61K 47/26
48
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Claims

Abstract

The present invention provides a gel patch comprising a base fabric, an adhesive layer, and a release liner in this order, wherein the adhesive layer contains a physiologically active substance, a water-soluble (meth)acrylic polymer, water, a surfactant, and poly(methyl acrylate/2-ethylhexyl acrylate), and the surfactant comprises a polyethylene glycol fatty acid ester or a polyoxyethylene sorbitan fatty acid ester.

Claims

exact text as granted — not AI-modified
1 . A gel patch comprising a base fabric, an adhesive layer, and a release liner in this order, wherein
 the adhesive layer comprises a physiologically active substance, a water-soluble (meth)acrylic polymer, water, a surfactant, and poly(methyl acrylate/2-ethylhexyl acrylate), and   the surfactant comprises a polyethylene glycol fatty acid ester or a polyoxyethylene sorbitan fatty acid ester.   
     
     
         2 . The gel patch according to  claim 1 , wherein the poly(methyl acrylate/2-ethylhexyl acrylate) is derived from a poly(methyl acrylate/2-ethylhexyl acrylate) emulsion. 
     
     
         3 . The gel patch according to  claim 1 , wherein the water-soluble (meth)acrylic polymer comprises polyacrylic acid or a neutralized polyacrylate. 
     
     
         4 . The gel patch according to  claim 1 , wherein
 the polyethylene glycol fatty acid ester comprises a monofatty acid ester of polyethylene glycol, and   the polyoxyethylene sorbitan fatty acid ester comprises a monofatty acid ester of polyoxyethylene sorbitan.   
     
     
         5 . The gel patch according to  claim 4 , wherein a fatty acid constituting the monofatty acid ester is a fatty acid having 12 to 18 carbon atoms. 
     
     
         6 . The gel patch according to  claim 5 , wherein the fatty acid having 12 to 18 carbon atoms comprises stearic acid or oleic acid. 
     
     
         7 . The gel patch according to  claim 2 , wherein the water-soluble (meth)acrylic polymer comprises polyacrylic acid or a neutralized polyacrylate. 
     
     
         8 . The gel patch according to  claim 2 , wherein
 the polyethylene glycol fatty acid ester comprises a monofatty acid ester of polyethylene glycol, and   the polyoxyethylene sorbitan fatty acid ester comprises a monofatty acid ester of polyoxyethylene sorbitan.   
     
     
         9 . The gel patch according to  claim 3 , wherein
 the polyethylene glycol fatty acid ester comprises a monofatty acid ester of polyethylene glycol, and   the polyoxyethylene sorbitan fatty acid ester comprises a monofatty acid ester of polyoxyethylene sorbitan.   
     
     
         10 . The gel patch according to  claim 7 , wherein
 the polyethylene glycol fatty acid ester comprises a monofatty acid ester of polyethylene glycol, and   the polyoxyethylene sorbitan fatty acid ester comprises a monofatty acid ester of polyoxyethylene sorbitan.   
     
     
         11 . The gel patch according to  claim 8 , wherein a fatty acid constituting the monofatty acid ester is a fatty acid having 12 to 18 carbon atoms. 
     
     
         12 . The gel patch according to  claim 9 , wherein a fatty acid constituting the monofatty acid ester is a fatty acid having 12 to 18 carbon atoms. 
     
     
         13 . The gel patch according to  claim 10 , wherein a fatty acid constituting the monofatty acid ester is a fatty acid having 12 to 18 carbon atoms. 
     
     
         14 . The gel patch according to  claim 11 , wherein the fatty acid having 12 to 18 carbon atoms comprises stearic acid or oleic acid. 
     
     
         15 . The gel patch according to  claim 12 , wherein the fatty acid having 12 to 18 carbon atoms comprises stearic acid or oleic acid. 
     
     
         16 . The gel patch according to  claim 13 , wherein the fatty acid having 12 to 18 carbon atoms comprises stearic acid or oleic acid.

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