Method and device for biomolecule preparation and detection using magnetic array

Abstract

An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises multiple zones such as a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.

We claim: 
     
         1 . A method of moving magnetic particles comprising
 providing magnetic particles in a fluidic network comprising a plurality of fluidic zones, and   activating a microcoil array functionally coupled to the network to thereby move the magnetic particles without active fluidic movement in the plurality of the fluidic zones.