Uses of hydroxybenzophenone in preparation of antiviral and antitumor drugs

Abstract

The present invention relates to uses of a benzophenone compound and analogues thereof having a symmetrical core structure and having same or different number of hydroxyl substitutions in benzene rings in the preparation of drugs for preventing and treating viral infections and anti-tumor drugs, in particular the use in the preparation of drugs for preventing and treating HIV, herpes virus and papillomavirus infection and the diseases induced thereby, wherein such viral infections include AIDS, genital warts, flat warts, common warts, herpes simplex, herpes zoster, vaginitis, cervicitis, cervical erosion and senile dementia, as well as cervical cancer, lung cancer, gastric cancer and colon cancer induced thereby, by means of preparing the hydroxy-substituted benzophenones and analogues thereof together with various compatible excipients into different medicaments or personal disinfected sanitary articles.

What is claimed is: 
     
         1 . Use of a hydroxy-substituted benzophenone compound in the preparation of drugs for prevention and treatment of viral infections and anti-tumor drugs, wherein the hydroxy-substituted benzophenone compound is a compound selected from the group consisting of 2,3,4,2′,3′,4′-hexahydroxybenzophenone, 2,3,4,2′,4′,5-hexahydroxybenzophenone and 3,4,5,2′,3′,4′,-hexahydroxybenzophenone. 
     
     
         2 . The use according to  claim 1 , wherein an effective amount of the compound and/or a composition containing the compound as an active ingredient are prepared together with various excipients for injections or oral preparations into power injections, water injections, infusions, tablets, capsules, granules or solutions. 
     
     
         3 . The use according to  claim 1 , an effective amount of the compound and/or a composition containing the compound as an active ingredient are prepared together with various compatible excipients for mucocutaneous preparations into pastes, gels, suppositories, tablets, lotions, films or sprays. 
     
     
         4 . The use according to  claim 1 , wherein an effective amount of the compound and/or a composition containing the compound as an active ingredient in are prepared together with various compatible excipients into anti-virus and anti-tumor products, wherein the anti-virus product is a product selected from the group of hand-washing lotions, bathing lotions, hand-washing soaps, bathing sponges, personal care wipers, facial tissues, intranasal sprays, mouthwashes, gynecological vaginal lotions, vaginal lubricants, contraceptives and combinations thereof. 
     
     
         5 . The use according to  claim 1 , wherein the use of the hydroxy-substituted benzophenone compound is characterized in that the hydroxy-substituted benzophenone compound is used in drugs for preventing and treating viral diseases and tumors. 
     
     
         6 . The use according to  claim 1 , wherein the viral infection is herpes virus, HIV and human papillomavirus infected by humans and animals. 
     
     
         7 . The use according to  claim 1 , wherein the use is in the preparation of drugs for preventing and treating mucocutaneous warts. 
     
     
         8 . The use according to  claim 1 , wherein the use is in the preparation of drugs for preventing and treating herpes virus-induced diseases. 
     
     
         9 . The use according to  claim 1 , wherein the use is in the preparation of drugs for preventing and treating lips herpes, genital herpes and herpes zoster. 
     
     
         10 . The use according to  claim 1 , wherein the use is in the preparation of drugs for preventing and treating herpes virus-induced senile dementia, and wherein the compound excludes 3,4,5,2′,3′,4′-hexahydroxybenzophenone. 
     
     
         11 . The use according to  claim 1 , wherein the use is in the preparation of drugs for removing or reducing human papillomavirus load and preventing the virus from inducing cancers. 
     
     
         12 . The use according to  claim 1 , wherein the use is in the preparation of drugs for removing or reducing human papillomavirus load and preventing the virus from inducing cervical cancer. 
     
     
         13 . The use according to  claim 1 , wherein the use is in the preparation of drugs for preventing and treating AIDS. 
     
     
         14 . The use according to  claim 1 , wherein the use is in the preparation of drugs for preventing and treating tumors. 
     
     
         15 . The use according to  claim 1 , wherein the use is in the preparation of drugs for preventing and treating cervical cancer. 
     
     
         16 . The use according to  claim 1 , wherein the use is in the preparation of drugs for preventing and treating gastrointestinal tumors.